Detection of proteins associated with extracellular matrix regulation in the aqueous humour of patients with primary glaucoma

S Nikhalashree, R George, B Shantha… - Current eye …, 2019 - Taylor & Francis
Purpose The protein composition of aqueous humour (AH) has held significant relevance
and remains to be the prime sample in the discovery of biomarkers in glaucoma. The …

[HTML][HTML] Analysis of protein composition of rabbit aqueous humor following two different cataract surgery incision procedures using 2-DE and LC-MS/MS

M Stastna, A Behrens, PJ McDonnell, JE Van Eyk - Proteome science, 2011 - Springer
Background The aqueous humor (AH), a liquid of the anterior and posterior chamber of the
eye, comprises many proteins with various roles and important biological functions. Many of …

Proteomic analysis of aqueous humor proteins associated with cataract development

Y Ji, X Rong, H Ye, K Zhang, Y Lu - Clinical biochemistry, 2015 - Elsevier
Background Cataract is one of the most common eye diseases that can further cause
blindness. Discovering susceptibility factors contributing to cataract development is helpful …

[HTML][HTML] New proteins as vascular biomarkers in primary open angle glaucomatous aqueous humor

SC Sacca, M Centofanti, A Izzotti - … ophthalmology & visual …, 2012 - iovs.arvojournals.org
Purpose: The aim of this study was to investigate the expression level of several biomarkers
in the in the aqueous humor of 14 patients with primary open angle glaucoma who …

[HTML][HTML] Serum and antibodies of glaucoma patients lead to changes in the proteome, especially cell regulatory proteins, in retinal cells

K Bell, S Funke, N Pfeiffer, FH Grus - 2012 - journals.plos.org
Purpose Previous studies show significantly specifically changed autoantibody reactions
against retinal antigens in the serum of glaucoma and ocular hypertension (OHT) patients in …

[HTML][HTML] Proteomic analysis of aqueous humor from patients with primary open angle glaucoma

X Duan, P Xue, N Wang, Z Dong, Q Lu, F Yang - Molecular vision, 2010 - ncbi.nlm.nih.gov
Purpose Primary open angle glaucoma (POAG) is a leading cause of irreversible blindness
on a global level. Researchers have yet to specify the exact mechanisms of POAG; the …

[HTML][HTML] Transthyretin and complex protein pattern in aqueous humor of patients with primary open-angle glaucoma

FH Grus, SC Joachim, S Sandmann, U Thiel… - Molecular …, 2008 - ncbi.nlm.nih.gov
Purpose To analyze protein patterns in the aqueous humor of glaucoma patients in
comparison to control subject using two different methods. Methods Aqueous humor was …

AHP DB: a reference database of proteins in the human aqueous humor

TJ Lee, A Goyal, G Jones, J Glass, V Doshi… - Database, 2024 - academic.oup.com
The aqueous humor (AH) is a low-viscosity biofluid that continuously circulates from the
posterior chamber to the anterior chamber of the eye. Recent advances in high-resolution …

Proteomic profiling reveals crucial retinal protein alterations in the early phase of an experimental glaucoma model

F Anders, J Teister, S Funke, N Pfeiffer, F Grus… - Graefe's Archive for …, 2017 - Springer
Purpose Clinical glaucoma is difficult to assess in terms of molecular pathophysiology,
prompting studies in experimental models of glaucoma. The purpose of this study was to …

From DNA damage to functional changes of the trabecular meshwork in aging and glaucoma

SC Saccà, S Gandolfi, A Bagnis, G Manni… - Ageing Research …, 2016 - Elsevier
Glaucoma is a degenerative disease of the eye. Both the anterior and posterior segments of
the eye are affected, extensive damage being detectable in the trabecular meshwork and …