Detection of proteins associated with extracellular matrix regulation in the aqueous humour of patients with primary glaucoma
Purpose The protein composition of aqueous humour (AH) has held significant relevance
and remains to be the prime sample in the discovery of biomarkers in glaucoma. The …
and remains to be the prime sample in the discovery of biomarkers in glaucoma. The …
[HTML][HTML] Analysis of protein composition of rabbit aqueous humor following two different cataract surgery incision procedures using 2-DE and LC-MS/MS
M Stastna, A Behrens, PJ McDonnell, JE Van Eyk - Proteome science, 2011 - Springer
Background The aqueous humor (AH), a liquid of the anterior and posterior chamber of the
eye, comprises many proteins with various roles and important biological functions. Many of …
eye, comprises many proteins with various roles and important biological functions. Many of …
Proteomic analysis of aqueous humor proteins associated with cataract development
Y Ji, X Rong, H Ye, K Zhang, Y Lu - Clinical biochemistry, 2015 - Elsevier
Background Cataract is one of the most common eye diseases that can further cause
blindness. Discovering susceptibility factors contributing to cataract development is helpful …
blindness. Discovering susceptibility factors contributing to cataract development is helpful …
[HTML][HTML] New proteins as vascular biomarkers in primary open angle glaucomatous aqueous humor
SC Sacca, M Centofanti, A Izzotti - … ophthalmology & visual …, 2012 - iovs.arvojournals.org
Purpose: The aim of this study was to investigate the expression level of several biomarkers
in the in the aqueous humor of 14 patients with primary open angle glaucoma who …
in the in the aqueous humor of 14 patients with primary open angle glaucoma who …
[HTML][HTML] Serum and antibodies of glaucoma patients lead to changes in the proteome, especially cell regulatory proteins, in retinal cells
K Bell, S Funke, N Pfeiffer, FH Grus - 2012 - journals.plos.org
Purpose Previous studies show significantly specifically changed autoantibody reactions
against retinal antigens in the serum of glaucoma and ocular hypertension (OHT) patients in …
against retinal antigens in the serum of glaucoma and ocular hypertension (OHT) patients in …
[HTML][HTML] Proteomic analysis of aqueous humor from patients with primary open angle glaucoma
Purpose Primary open angle glaucoma (POAG) is a leading cause of irreversible blindness
on a global level. Researchers have yet to specify the exact mechanisms of POAG; the …
on a global level. Researchers have yet to specify the exact mechanisms of POAG; the …
[HTML][HTML] Transthyretin and complex protein pattern in aqueous humor of patients with primary open-angle glaucoma
FH Grus, SC Joachim, S Sandmann, U Thiel… - Molecular …, 2008 - ncbi.nlm.nih.gov
Purpose To analyze protein patterns in the aqueous humor of glaucoma patients in
comparison to control subject using two different methods. Methods Aqueous humor was …
comparison to control subject using two different methods. Methods Aqueous humor was …
AHP DB: a reference database of proteins in the human aqueous humor
The aqueous humor (AH) is a low-viscosity biofluid that continuously circulates from the
posterior chamber to the anterior chamber of the eye. Recent advances in high-resolution …
posterior chamber to the anterior chamber of the eye. Recent advances in high-resolution …
Proteomic profiling reveals crucial retinal protein alterations in the early phase of an experimental glaucoma model
F Anders, J Teister, S Funke, N Pfeiffer, F Grus… - Graefe's Archive for …, 2017 - Springer
Purpose Clinical glaucoma is difficult to assess in terms of molecular pathophysiology,
prompting studies in experimental models of glaucoma. The purpose of this study was to …
prompting studies in experimental models of glaucoma. The purpose of this study was to …
From DNA damage to functional changes of the trabecular meshwork in aging and glaucoma
SC Saccà, S Gandolfi, A Bagnis, G Manni… - Ageing Research …, 2016 - Elsevier
Glaucoma is a degenerative disease of the eye. Both the anterior and posterior segments of
the eye are affected, extensive damage being detectable in the trabecular meshwork and …
the eye are affected, extensive damage being detectable in the trabecular meshwork and …