[HTML][HTML] Correlation of aqueous, vitreous, and serum protein levels in patients with retinal diseases

S Wilson, J Siebourg-Polster, B Titz… - … vision science & …, 2023 - iovs.arvojournals.org
Purpose: To further establish aqueous humor (AH) as a clinically suitable source of protein
biomarkers in retinal diseases by evaluating the correlation of a large panel of proteins …

Human aqueous humor proteome in cataract, glaucoma, and pseudoexfoliation syndrome

AA Kliuchnikova, NI Samokhina, IY Ilina… - …, 2016 - Wiley Online Library
Twenty‐nine human aqueous humor samples from patients with eye diseases such as
cataract and glaucoma with and without pseudoexfoliation syndrome were characterized by …

[HTML][HTML] Analysis of the aqueous humor proteome in patients with age-related macular degeneration

B Rinsky, G Beykin, M Grunin, R Amer… - … & Visual Science, 2021 - iovs.arvojournals.org
Purpose: Age-related macular degeneration (AMD) is associated with altered gene and
protein expression in the retina. We characterize the aqueous humor (AH) proteome in AMD …

[HTML][HTML] Comprehensive proteomic profiling of aqueous humor proteins in proliferative diabetic retinopathy

H Xiao, W Xin, LM Sun, SS Li… - … Vision Science & …, 2021 - iovs.arvojournals.org
Purpose: Proliferative diabetic retinopathy (PDR) is a serious ocular disease that can lead to
retinal microvascular complications in patients with diabetes mellitus. To date, no studies …

[HTML][HTML] New biomarker combination related to oxidative stress and inflammation in primary open-angle glaucoma

A Dammak, J Sanchez Naves, F Huete-Toral… - Life, 2023 - mdpi.com
Glaucoma is a multifactorial neurodegenerative disease and the second leading cause of
blindness. Detection of clinically relevant biomarkers would aid better diagnoses and …

Identification of differentially expressed proteins in the aqueous humor of primary congenital glaucoma

RA Bouhenni, S Al Shahwan, J Morales… - Experimental eye …, 2011 - Elsevier
Primary Congenital Glaucoma (PCG) is an autosomal recessive disease caused by an
abnormal development of the anterior chamber angle. Although, PCG has been linked to …

[HTML][HTML] Link between neurodegeneration and trabecular meshwork injury in glaucomatous patients

Y Zhang, Q Yang, F Guo, X Chen, L Xie - BMC ophthalmology, 2017 - Springer
Background Glaucoma is classified as a neurodegenerative disease. However, the
biomarkers of neurodegeneration in the aqueous humour of primary open angle glaucoma …

The Human Eye Proteome Project: perspectives on an emerging proteome

RD Semba, JJ Enghild, V Venkatraman… - …, 2013 - Wiley Online Library
There are an estimated 285 million people with visual impairment worldwide, of whom 39
million are blind. The pathogenesis of many eye diseases remains poorly understood. The …

Aqueous humor protein dysregulation in primary angle-closure glaucoma

SS Adav, J Wei, J Qian, NYA Gan, LWL Yip… - International …, 2019 - Springer
Purpose Primary angle-closure glaucoma (PACG) is associated with increased intraocular
pressure, optic nerve damage, and progressive vision loss, but the molecular mechanism …

[HTML][HTML] Proteomics analysis of molecular risk factors in the ocular hypertensive human retina

X Yang, G Hondur, M Li, J Cai, JB Klein… - … & visual science, 2015 - arvojournals.org
Purpose: To better understand ocular hypertension–induced early molecular alterations that
may determine the initiation of neurodegeneration in human glaucoma, this study analyzed …