Defining the metabolic programs that underlie stem cell maintenance will be essential for
developing strategies to manipulate stem cell capacity. Mammalian hematopoietic stem cells …

Single cell PCR studies showed that hematopoietic stem cells (HSCs) express a variety of
lineage-affiliated genes. However, it remains unclear whether these cells exhibiting" lineage …

Hematopoietic stem cells (HSCs), which govern the production of all blood lineages,
transition through a series of functional states characterized by expansion during fetal …

Hematopoietic stem and progenitor cell (HSPC) homeostasis declines with age, leading to
impaired hematopoiesis. Mesenchymal stromal cells (MSC) are critical components of the …

It is critical to understand how human quiescent long-term hematopoietic stem cells (LT-
HSCs) sense demand from daily and stress-mediated cues and then transition into …

Haematopoietic stem cells (HSCs) self-renew for life, thereby making them one of the few
blood cells that truly age,. Paradoxically, although HSCs numerically expand with age, their …

Hematopoietic stem cells (HSCs) are the rare cells from which all hematopoietic cells are
derived. The absence of HSCs is not compatible with life because many essential cells, such …

Haematopoietic stem cells (HSCs) are derived early from embryonic precursors, such as
haemogenic endothelial cells and pre-haematopoietic stem cells (pre-HSCs), the molecular …

Hematopoietic stem cells (HSCs) reside in the bone marrow (BM) niche in a noncycling state
and enter the cell cycle at long intervals. However, little is known about inter‐and …

Hematopoietic stem cells (HSCs) ensure a balanced production of all blood cells throughout
life. As they age, HSCs gradually lose their self-renewal and regenerative potential, whereas …