OBJECTIVE To describe current data evaluating the effect of vitamin A intake on fracture
risk. DATA SOURCES A literature search using MEDLINE (1966–March 2005) was …

Severe vitamin A toxicity is known to have adverse effects on skeletal health. Studies
involving animal models and case reports have documented that hypervitaminosis A is …

Results from observational studies of the association between vitamin A intake or serum
concentration and bone mineral density or fracture are mixed. The inconsistencies may be …

Abstract Effects of toxic amounts of vitamin A include skeletal effects; from acute toxic
exposure to chronic high-dose intake of vitamin A, these effects have led experts to …

Excessive intake of vitamin A is postulated to have a detrimental effect on bone by inducing
osteoporosis. This may lead to an increased risk of fracture, particularly in persons who are …

Background Excessive intakes of vitamin A have been shown to have adverse skeletal
effects in animals. High vitamin A intake may lead to an increased risk of fracture in humans …

VITAMIN A, an essential micronutrient, is provided by animal foods, whereas-carotene and
other carotenoids, known as provitamin A molecules, are derived from plant sources. In …

In recent studies from Sweden and the United States, a high vitamin A intake has been
associated with low bone mineral density (BMD) and increased fracture risk. In Sweden and …

BACKGROUND: Recent studies on the association between vitamin A and fracture risk have
focused on samples with high vitamin A intake. We analyzed a cohort that was more …

Osteoporotic fracture is a significant cause of morbidity and mortality and is a challenging
global health problem. Previous reports of the relation between vitamin A intake or blood …