Nephrolithiasis is a common and frequently-occurring disease in the urinary system with
high recurrence. The present study aimed to explore the protective effect and underlying …

Background. Nephrolithiasis is a common disease that seriously affects the health and life
quality of patients. Despite the reported effect of hyperoside (Hyp) against nephrolithiasis …

Objective: The study aimed to evaluate the preventive effects of hydroxycitric acid (HCA) for
stone formation in the glyoxylate-induced mouse model. Materials and Methods: Male …

Background High prevalence and reoccurrence rate of nephrolithiasis bring about serious
socioeconomic and healthcare burden, necessitating the need of effective therapeutic …

Kidney stone is a urinary system disease with a high incidence, and effective stone drugs
are limited. Hydroxycitric acid (HCA), mainly found in Garcinia cambogia and Hibiscus …

Background and objective Renal tissue injuries by free radicals are an essential reason in
pathogenesis of urinary tract stones. Ethylene glycol is one of the toxic agents which can …

Calcium oxalate (CaOx) is the most common type of urinary stone. Increase of ROS and
NADPH oxidase gives rise to inflammation and injury of renal tubular cells, which promotes …

Calcium oxalate (CaOx) is the most common component of kidney stones. Oxidative stress,
inflammation and autophagy-induced cell death are the major causes of CaOx crystal …

Oxidative stress is a major risk factor for calcium oxalate nephrolithiasis. Reports suggest
that oxidative stress response is induced in animals and humans with kidney stones. Keap1 …

The aim of the study is to investigate the effects of pentoxifylline (PTX) on the renal tubular
cell injury and stone formation in a hyperoxaluric rat model induced by ethylene glycol and …