Pathognomonic neuroradiological signs in Wilson's disease–Truth or myth?

B Rędzia-Ogrodnik, A Członkowska, A Antos… - Parkinsonism & Related …, 2023 - Elsevier
Introduction Wilson's disease (WD) is a treatable genetic disorder caused by impaired
copper metabolism. Early diagnosis and correct anti-copper treatment are crucial for …

Clinical correlation of brain MRI and MRS abnormalities in patients with Wilson disease

RA Page, CA Davie, D MacManus, KA Miszkiel… - Neurology, 2004 - AAN Enterprises
Background: The progression of Wilson disease (WD), a disorder of copper metabolism, can
be arrested by chelation therapy. However, neurologic deficits may persist despite adequate …

MR imaging of the brain in neurologic Wilson disease

XE Yu, S Gao, RM Yang… - American Journal of …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Neurologic Wilson disease is an inherited disease
characterized by a copper metabolic disorder that causes damage to many organs …

Prognostic significance of neurologic examination findings in Wilson disease

JF Burke, P Dayalu, B Nan, F Askari, GJ Brewer… - Parkinsonism & related …, 2011 - Elsevier
BACKGROUND: Wilson disease patients present with any of several neurologic
phenotypes, and their treated outcomes vary widely. Our goal was to determine whether …

Prevalence and features of non-motor symptoms in Wilson's disease

GR Palmieri, G De Michele, M Matarazzo… - Parkinsonism & Related …, 2022 - Elsevier
Abstract Introduction Wilson's Disease (WD) is an autosomal recessive disorder caused by
excessive copper deposition in liver, brain and other organs. The clinical picture is …

[HTML][HTML] Brain Magnetic Resonance Imaging in Wilson's Disease—Significance and Practical Aspects—A Narrative Review

T Litwin, B Rędzia-Ogrodnik, A Antos, A Przybyłkowski… - Brain Sciences, 2024 - mdpi.com
Wilson's disease (WD) is a genetic disorder of copper metabolism with pathological copper
accumulation in many organs, resulting in clinical symptoms, mostly hepatic and …

[HTML][HTML] Neurologic impairment in Wilson disease

P Dusek, T Litwin, A Członkowska - Annals of translational …, 2019 - ncbi.nlm.nih.gov
Neurologic symptoms in Wilson disease (WD) appear at an older age compared to hepatic
symptoms and manifest in patients with misdiagnosed liver disease, in patients when the …

Six-year clinical and MRI quantitative susceptibility mapping (QSM) follow-up in neurological Wilson's disease under zinc therapy: a case report

D Zaino, I Chiarotti, C Battisti, S Salvatore… - Neurological …, 2019 - Springer
Wilson's disease (WD) is an inherited disorder of copper metabolism, resulting in
pathological accumulation of copper, principally in the liver, brain and cornea. The causative …

Subclinical neurological involvement does not develop if Wilson's disease is treated early

R Dubbioso, G Ranucci, M Esposito, F Di Dato… - Parkinsonism & Related …, 2016 - Elsevier
Background & aims Wilson's disease (WD) is a genetic disorder of copper metabolism
causing dysfunctions of various organs, mostly the liver and brain. If untreated, WD is fatal …

Wilson's disease: two treatment modalities. Correlations to pretreatment and posttreatment brain MRI

MD Leiros da Costa, M Spitz, LA Bacheschi, CC Leite… - Neuroradiology, 2009 - Springer
Introduction Brain magnetic resonance imaging (MRI) studies on Wilson's disease (WD)
show lack of correlations between neurological and neuroimaging features. Long-term …