Purpose The use of hypertonic saline injection in trauma patients is discussed. Summary
Patients with hemorrhage, burns, and traumatic brain injury (TBI) may develop hypovolemic …

The optimal fluid for the resuscitation of critically ill and injured patients remains the subject
of considerable controversy. Hypertonic crystalloid solutions such as hypertonic saline …

The early management of patients who have sustained traumatic brain injury is aimed at
preventing secondary brain injury through avoidance of cerebral hypoxia and …

Objective: To discuss the reasons why 250 ml 7.5% hypertonic saline was chosen as a pre-
hospital resuscitation fluid for head injured patients in a multicentred, prospective …

Background: Published experience of hypertonic saline (HTS) use in resuscitation has
described the use of commercially unavailable 7.5% solutions. The purpose of this study …

Literature suggest that hypertonic saline (HTS) solution with sodium chloride concentration
greater than the physiologic 0.9% can be useful in controlling elevated intracranial pressure …

ObjectivesHypertonic saline solutions are increasingly used to treat increased intracranial
pressure following severe traumatic brain injury. However, whether hypertonic saline …

Background The optimal prehospital fluid for the treatment of hypotension is unknown.
Hypertonic fluids may increase circulatory volume and mute the pro-inflammatory response …

Background Clinical trials evaluating the use of hypertonic saline in the treatment of
hypovolemia and head trauma suggest no survival superiority over normal saline; however …

The past decade has witnessed a resurgence of interest in the use of hypertonic saline for
low-volume resuscitation after trauma. Preliminary studies suggested that benefits are …