Background: The adipocyte derived hormone, leptin, has cytokine like function and may
mediate the effects of starvation on immunity. Mice with congenital leptin deficiency (ob/ob) …

Circulating leptin levels, proinflammatory and T helper cells type 1 (Th1), Th2 cytokine
production, and lymphoproliferative response were measured in 15 infants with primary …

Malnutrition compromises immune function, resulting in reduced resistance to infection.
Recent animal and human studies have suggested that leptin is capable of modulating the …

Background: Most human research on leptin has involved well-nourished subjects or clinical
states such as anorexia nervosa or cancer cachexia. Objective: We studied the development …

Leptin is an adipocyte-secreted hormone which plays a key role in energy homeostasis. Our
aim was to determine the relationship between serum leptin and clinical and biochemical …

Leptin, the protein product of the obesity gene, produced by adipose tissue, regulates body
weight and energy expenditure through CNS feedback mechanisms. In obesity, leptin levels …

A negative correlation between leptin and appetite or food intake has been shown in healthy
individuals. However, the role of leptin in clinical conditions characterized by anorexia has …

Objectives:(1) To investigate normal circulating levels of leptin in children at various stages
of pubertal maturation (Tanner stages) according to sex; and (2) to analyze serum leptin …

Objective. We studied whether the serum leptin concentration at age 2 years predicts
changes in relative body weight by age 8 and whether the serum leptin concentration is …

Leptin, the product of the ob gene, is a hormone secreted by adipocytes that is known to
decrease food intake and increase energy expenditure in ob/ob mice. In humans, variants in …