Increased cryptococcal meningitis mortality among HIV negative, non-transplant patients: a single US center cohort study

G Motoa, A Pate, D Chastain, S Mann… - Therapeutic …, 2020 - journals.sagepub.com
Cryptococcal meningitis (CM) is an opportunistic fungal infection associated with human
immunodeficiency virus (HIV) and other forms of immunosuppression. We lack a clear …

Cryptococcal meningitis in young, immunocompetent patients: a single-center retrospective case series and review of the literature

M Stack, J Hiles, E Valinetz, SK Gupta… - Open Forum …, 2023 - academic.oup.com
Background Cryptococcal meningitis is an uncommon but serious infection with high
mortality and morbidity. Classically described in immunocompromised patients, including …

Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis: a randomized controlled trial

JN Jarvis, G Meintjes, K Rebe, GN Williams, T Bicanic… - Aids, 2012 - journals.lww.com
Background: Interferon-gamma (IFNγ) is of key importance in the immune response to
Cryptococcus neoformans. Mortality related to cryptococcal meningitis remains high, and …

Long-term mortality and disability in cryptococcal meningitis: a systematic literature review

E Pasquier, J Kunda, P De Beaudrap… - Clinical Infectious …, 2018 - academic.oup.com
Cryptococcal meningitis (CM) is the primary cause of meningitis in adults with human
immunodeficiency virus (HIV) infection and an emerging disease in HIV-seronegative …

Prediction of unfavorable outcomes in cryptococcal meningitis: results of the multicenter Infectious Diseases International Research Initiative (ID-IRI) cryptococcal …

IN Hakyemez, H Erdem, G Beraud, M Lurdes… - European journal of …, 2018 - Springer
Cryptococcal meningitis (CM) is mostly seen in immunocompromised patients, particularly
human immunodeficiency virus (HIV)-positive patients, but CM may also occur in apparently …

Cryptococcal infections: changing epidemiology and implications for therapy

RM La Hoz, PG Pappas - Drugs, 2013 - Springer
Although the incidence of HIV-associated cryptococcosis has decreased in developed
countries since the introduction of antiretroviral therapy, this disease continues to cause …

Cryptococcosis in the developing world: an elephant in the parlor

PG Pappas - Clinical infectious diseases, 2010 - academic.oup.com
Central nervous system cryptococcosis occurs in an estimated 1 million persons in the world
each year, most of whom are human immunodeficiency virus (HIV) positive and reside in …

Management of cryptococcal meningitis in sub-Saharan Africa

A Jackson, MC Hosseinipour - Current HIV/AIDS Reports, 2010 - Springer
Cryptococcal meningitis (CM) is a common form of meningitis in sub-Saharan Africa due to
the high prevalence of HIV/AIDS. This report outlines the management of CM with a focus on …

Cryptococcosis and cryptococcal meningitis: New predictors and clinical outcomes at a United States academic medical centre

BH Kashef Hamadani, C Franco‐Paredes… - Mycoses, 2018 - Wiley Online Library
As the diagnosis of cryptococcosis is challenging in low‐prevalence settings, uncovering
predictive factors can improve early diagnosis and timely treatment. The aim of the study …

Cryptococcal meningitis: a review of cryptococcal antigen screening programs in Africa

G Greene, DS Lawrence, A Jordan… - Expert review of anti …, 2021 - Taylor & Francis
Introduction Cryptococcal meningitis remains a significant contributor to AIDS-related
mortality despite widened access to antiretroviral therapy. Cryptococcal antigen (CrAg) can …