Ticagrelor

K Huber, B Hamad, P Kirkpatrick - Nature Reviews Drug Discovery, 2011 - go.gale.com
Ticagrelor (Brilique; AstraZeneca), an oral antiplatelet therapy, was granted marketing
authorization by the European Commission in December 2010 for the prevention of …

[HTML][HTML] Clinical efficacy of ticagrelor in patients undergoing emergency intervention for acute myocardial infarction and its impact on platelet aggregation rate

HB Wu, HP Tian, XC Wang, SR Bai, XN Li… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Objective: This study aims to investigate the clinical efficacy of ticagrelor in patients who
underwent emergency percutaneous coronary intervention (PCI) for acute myocardial …

Ticagrelor versus clopidogrel in East Asian patients with acute coronary syndrome: systematic review and meta-analysis

N Misumida, S Aoi, SM Kim, KM Ziada… - Cardiovascular …, 2018 - Elsevier
Background Bleeding complications are associated with unfavorable outcomes in patients
with acute coronary syndrome (ACS). Compared to Whites, several studies demonstrated a …

[HTML][HTML] Ticagrelor or prasugrel in patients with acute coronary syndromes

S Schüpke, FJ Neumann, M Menichelli… - … England Journal of …, 2019 - Mass Medical Soc
Background The relative merits of ticagrelor as compared with prasugrel in patients with
acute coronary syndromes for whom invasive evaluation is planned are uncertain. Methods …

Ticagrelor overcomes high platelet reactivity in patients with acute myocardial infarction or coronary artery in-stent restenosis: a randomized controlled trial

P Li, Y Yang, T Chen, Y Liu, A Cao, J Liu, Z Wang… - Scientific Reports, 2015 - nature.com
High on-treatment platelet reactivity (HTPR) is accompanied by an increased risk of adverse
outcomes. Direct comparison of the antiplatelet effects between ticagrelor and high-dose …

Clinical outcomes after ticagrelor and clopidogrel in Chinese post-stented patients

Y Sun, C Li, L Zhang, T Yu, H Ye, B Yu, M Tao, J Jiang… - Atherosclerosis, 2019 - Elsevier
Background and aims International guidelines recommend ticagrelor over clopidogrel as
preferred antiplatelet agent in patients following coronary stenting. However, no large real …

Ticagrelor with or without aspirin in chinese patients undergoing percutaneous coronary intervention: a TWILIGHT China substudy

Y Han, BE Claessen, SL Chen… - Circulation …, 2022 - Am Heart Assoc
Background: The risk/benefit tradeoff of dual antiplatelet therapy after percutaneous
coronary intervention may vary in East Asian patients as compared with their non-East Asian …

Ticagrelor: a safe and effective approach for overcoming clopidogrel resistance in patients with stent thrombosis?

M Samoš, M Fedor, F Kovár, L Duraj… - Blood Coagulation & …, 2016 - journals.lww.com
Stent thrombosis is a morbid complication following percutaneous coronary intervention
(PCI). Dual antiplatelet therapy significantly reduces stent thrombosis risk. However, the …

The clinical efficacy and safety evaluation of ticagrelor for acute coronary syndrome in general ACS patients and diabetic patients: A systematic review and meta …

Q Tan, X Jiang, S Huang, T Zhang, L Chen, S Xie… - PloS one, 2017 - journals.plos.org
Objective In this study, a systematic evaluation was conducted to estimate the efficacy and
safety of ticagrelor for treating acute coronary syndrome (ACS) in general ACS patients and …

Low-dose ticagrelor yields an antiplatelet efficacy similar to that of standard-dose ticagrelor in healthy subjects: an open-label randomized controlled trial

P Li, Y Gu, Y Yang, L Chen, J Liu, L Gao, Y Qin… - Scientific Reports, 2016 - nature.com
Ticagrelor has a greater antiplatelet efficacy than clopidogrel but may be accompanied by
an increased risk of bleeding. This study evaluated the antiplatelet effect and …