CE–MS-based urinary biomarkers to distinguish non-significant from significant prostate cancer

M Frantzi, E Gomez Gomez… - British journal of …, 2019 - nature.com
Background Prostate cancer progresses slowly when present in low risk forms but can be
lethal when it progresses to metastatic disease. A non-invasive test that can detect …

Validation of diagnostic nomograms based on CE–MS urinary biomarkers to detect clinically significant prostate cancer

M Frantzi, I Heidegger, MC Roesch… - World Journal of …, 2022 - Springer
Abstract Purpose Prostate cancer (PCa) is one of the most common cancers and one of the
leading causes of death worldwide. Thus, one major issue in PCa research is to accurately …

Mass spectrometry-based biomarkers to detect prostate cancer: a multicentric study based on non-invasive urine collection without prior digital rectal examination

M Frantzi, Z Culig, I Heidegger, M Mokou, A Latosinska… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer is the most frequent cancer type and one of the leading
causes of death in men globally. Multiple biomarkers analyzed in urine have been proposed …

Detection of high-grade prostate cancer using a urinary molecular biomarker–based risk score

L Van Neste, RJ Hendriks, S Dijkstra, G Trooskens… - European urology, 2016 - Elsevier
Background To reduce overdiagnosis and overtreatment, a test is urgently needed to detect
clinically significant prostate cancer (PCa). Objective To develop a multimodal model …

[HTML][HTML] Urinary markers aiding in the detection and risk stratification of prostate cancer

N Raja, CM Russell, AK George - Translational andrology and …, 2018 - ncbi.nlm.nih.gov
The purpose of this review is to highlight the role of existing and promising urinary
biomarkers for the detection and prognostication of prostate cancer (PCa). A number of …

A multiplex model of combining gene‐based, protein‐based, and metabolite‐based with positive and negative markers in urine for the early diagnosis of prostate …

DL Cao, DW Ye, HL Zhang, Y Zhu, YX Wang… - The …, 2011 - Wiley Online Library
BACKGROUND Multiplex urine‐based assay emerged outperforms single biomarker (eg,
prostate‐specific antigen, PSA) for predicting prostate cancer (CaP), whereas its combined …

[HTML][HTML] Biomarkers for detection of clinically significant prostate cancer: contemporary clinical data and future directions

NW Eyrich, TM Morgan, JJ Tosoian - Translational Andrology and …, 2021 - ncbi.nlm.nih.gov
Use of serum prostate-specific antigen (PSA) testing for early detection of prostate cancer
appears to reduce cancer-specific mortality. Due to the limited specificity of PSA for clinically …

New developments in prostate cancer biomarkers

NE Martin - Current Opinion in Oncology, 2016 - journals.lww.com
Over the past several years, the management of localized prostate cancer has seen the
development of several novel biomarkers aimed at improving decision making. Although a …

Development and Clinical Validation of an In Situ Biopsy-Based Multimarker Assay for Risk Stratification in Prostate Cancer

P Blume-Jensen, DM Berman, DL Rimm… - Clinical cancer …, 2015 - AACR
Purpose: Prostate cancer aggressiveness and appropriate therapy are routinely determined
following biopsy sampling. Current clinical and pathologic parameters are insufficient for …

A panel of biomarkers for diagnosis of prostate cancer using urine samples

J Guo, J Yang, X Zhang, X Feng, H Zhang… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Prostate cancer (PCa) diagnosis using patient urine samples represents a
non-invasive and more convenient method than the conventional biopsy and prostate …