Signal transducers and activators of transcription (STATs) mediate essential signaling
pathways in different biological processes, including immune responses, hematopoiesis …

Abstract The Signal Transducer and Activator of Transcription (STAT) family of proteins
consists of transcription factors that play a complex and essential role in the regulation of …

Signal transducer and activator of transcription (STAT) proteins are latent transcription
factors that reside in the cytoplasm of several types of cells. In canonical signaling, upon …

Signal transducer and activator of transcription (STAT) 3 is one of the most complex
regulators of transcription. Constitutive activation of STAT3 has been reported in many types …

Signal transducer and activator of transcription 3 (STAT3), a member of the STAT family,
discovered in the cytoplasm of almost all types of mammalian cells, plays a significant role in …

STATs are a family of transcription factors that regulate many critical cellular processes such
as proliferation, apoptosis, and differentiation. Dysregulation of STATs is frequently …

Signal transducers and activators of transcription 3 (STAT-3) is a transcription factor that
regulates the gene expression of several target genes. These factors are activated by the …

Signal transducer and activator of transcription 3 (STAT3) is a transcriptional factor involved
in almost all cancer hallmark features including tumor proliferation, metastasis …

The oncogenic transcription factor STAT3 is inappropriately activated in multiple
hematopoietic and solid malignancies, in which it drives the expression of genes involved in …

STATs constitute a large family of transcription activators and transducers of signals that
have an important role in many cell functions as regulation of proliferation and differentiation …