Ferroptosis is widely present in fibrosis-related diseases. The basic pathology of premature
ovarian insufficiency (POI) involves ovarian tissue fibrosis, and there are currently fewer …

Chemotherapy was conventionally applied to kill cancer cells, but regrettably, they also
induce damage to normal cells with high-proliferative capacity resulting in cardiotoxicity …

Ferroptosis, a form of regulated cell death, was first defined in 2012. Ferroptosis mainly
involves iron-driven lipid peroxidation damage of cells. This process is regulated by iron …

Ovarian cancer (OVCA) is one of the most lethal malignancies with a five-year relative
survival below 50% by virtue of its high recurrence rate and inadequate early detection …

Ferroptosis is a novel kind of regulated cell death distinct from autophagy, apoptosis, and
necrosis; it is predominantly caused by the iron-dependent lipid peroxidation. According to …

Polycystic ovary syndrome is one of the most common endocrine and metabolic
gynecological disorders, of which dysfunction of ovarian granulosa cells is a key contributing …

Ferroptosis is a novel type of regulated cell death driven by iron-dependent lipid
peroxidation, which is distinguished from traditional types of programmed cell death, such as …

Cyclophosphamide (CP) is a widely used chemotherapeutic drug and immunosuppressant
in the clinic, and the hypoandrogenism caused by CP is receiving more attention. Some …

Reprogramming of lipid metabolism, which modulates energy utilization and cell signaling,
maintains cell survival and promotes cancer metastasis in cancer cells. Ferroptosis is a type …

Objectives Developing novel therapeutic approaches to defeat chemoresistance is the major
goal of ovarian cancer research. Induction of ferroptosis has shown promising antitumor …