Particle size dependent deposition and pulmonary inflammation after short-term inhalation of silver nanoparticles

HM Braakhuis, I Gosens, P Krystek, JAF Boere… - Particle and fibre …, 2014 - Springer
Background Although silver nanoparticles are currently used in more than 400 consumer
products, it is not clear to what extent they induce adverse effects after inhalation during …

Identification of the appropriate dose metric for pulmonary inflammation of silver nanoparticles in an inhalation toxicity study

HM Braakhuis, FR Cassee, PHB Fokkens… - …, 2016 - Taylor & Francis
A number of studies have shown that induction of pulmonary toxicity by nanoparticles of the
same chemical composition depends on particle size, which is likely in part due to …

Influence of particle size on persistence and clearance of aerosolized silver nanoparticles in the rat lung

DS Anderson, ES Patchin, RM Silva… - Toxicological …, 2015 - academic.oup.com
The growing use of silver nanoparticles (AgNPs) in consumer products raises concerns
about potential health effects. This study investigated the persistence and clearance of 2 …

Nanosilver induces minimal lung toxicity or inflammation in a subacute murine inhalation model

LV Stebounova, A Adamcakova-Dodd, JS Kim… - Particle and fibre …, 2011 - Springer
Background There is increasing interest in the environmental and health consequences of
silver nanoparticles as the use of this material becomes widespread. Although human …

Pulmonary effects of silver nanoparticle size, coating, and dose over time upon intratracheal instillation

RM Silva, DS Anderson, LM Franzi… - Toxicological …, 2015 - academic.oup.com
Abstract Silver nanoparticles (Ag NPs) can be found in myriad consumer products, medical
equipment/supplies, and public spaces. However, questions remain regarding the risks …

Persistence of silver nanoparticles in the rat lung: Influence of dose, size, and chemical composition

DS Anderson, RM Silva, D Lee, PC Edwards… - …, 2015 - Taylor & Francis
Increasing silver nanoparticle (AgNP) use in sprays, consumer products, and medical
devices has raised concerns about potential health effects. While previous studies have …

Lung function changes in Sprague-Dawley rats after prolonged inhalation exposure to silver nanoparticles

JH Sung, JH Ji, JU Yoon, DS Kim, MY Song… - Inhalation …, 2008 - Taylor & Francis
The antimicrobial activity of silver nanoparticles has resulted in their widespread use in
many consumer products. However, despite the continuing increase in the population …

Subchronic inhalation toxicity of silver nanoparticles

JH Sung, JH Ji, JD Park, JU Yoon, DS Kim… - Toxicological …, 2009 - academic.oup.com
The subchronic inhalation toxicity of silver nanoparticles was studied in Sprague-Dawley
rats. Eight-week-old rats, weighing approximately 253.2 g (males) and 162.6 g (females) …

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

AR Gliga, S Skoglund, I Odnevall Wallinder… - Particle and fibre …, 2014 - Springer
Abstract Background Silver nanoparticles (AgNPs) are currently one of the most
manufactured nanomaterials. A wide range of toxicity studies have been performed on …

Recovery from silver-nanoparticle-exposure-induced lung inflammation and lung function changes in Sprague Dawley rats

KS Song, JH Sung, JH Ji, JH Lee, JS Lee, HR Ryu… - …, 2013 - Taylor & Francis
In a previous study, the lung function, as indicated by the tidal volume, minute volume, and
peak inspiration flow, decreased during 90 days of exposure to silver nanoparticles and was …