Background Calcitonin gene-related peptide is recognized as a key player in migraine, yet
the mechanisms and sites of calcitonin gene-related peptide action remain unknown. The …

The neuropeptide calcitonin gene-related peptide (CGRP) is a key player in migraine.
Although migraine can be treated using CGRP antagonists that act peripherally, the relevant …

Calcitonin gene-related peptide (CGRP) was first discovered in the 1980s as a splice variant
from the calcitonin gene. Since its discovery, its role in migraine pathophysiology has been …

Objective To evaluate whether intraganglionic calcitonin gene-related peptide induced
differential migraine-like responses in male and female rats. Methods Calcitonin gene …

Migraine is the third most common disease in the world (behind dental caries and tension-
type headache) with an estimated global prevalence of 15%, yet its etiology remains poorly …

Migraine is a chronic neurological disorder characterized by recurrent episodes of severe
unilateral throbbing head pain and associated symptoms, such as photophobia. Our current …

The neuropeptide calcitonin gene-related peptide (CGRP) plays a critical role in the
pathophysiology of migraine. We have focused on the role of CGRP in photophobia, which …

The neuropeptide calcitonin gene-related peptide (CGRP) is a major player in migraine
pathophysiology. Previous preclinical studies demonstrated that intracerebroventricular …

The neuropeptide calcitonin gene-related peptide (CGRP) plays a key role in migraine.
However, a major challenge for studying CGRP actions is the lack of animal models for …

Migraine is a neurological disorder that is far more than just a bad headache. A hallmark of
migraine is altered sensory perception. A likely contributor to this altered perception is the …