Considerations for empiric antimicrobial therapy in sepsis and septic shock in an era of antimicrobial resistance

JR Strich, EL Heil, H Masur - The Journal of Infectious Diseases, 2020 - academic.oup.com
Patients with sepsis present across a spectrum of infection sites and severity of illnesses
requiring complex decision making at the bedside as to when prompt antibiotics are …

Sepsis and septic shock: selection of empiric antimicrobial therapy

BA Cunha - Critical care clinics, 2008 - Elsevier
This article is a brief overview of empiric antibiotic selection for sepsis and septic shock. The
article includes a differential diagnosis of the mimics of sepsis and stresses a strategy for …

Bench-to-bedside review: appropriate antibiotic therapy in severe sepsis and septic shock–does the dose matter?

F Pea, P Viale - Critical Care, 2009 - Springer
Appropriate antibiotic therapy in patients with severe sepsis and septic shock should mean
prompt achievement and maintenance of optimal exposure at the infection site with broad …

Antimicrobial therapy for patients with severe sepsis and septic shock: an evidence-based review

PY Bochud, M Bonten, O Marchetti… - Critical care …, 2004 - journals.lww.com
Objective: In 2003, critical care and infectious disease experts representing 11 international
organizations developed management guidelines for antimicrobial therapy for patients with …

Antibiotics for sepsis—finding the equilibrium

M Klompas, T Calandra, M Singer - Jama, 2018 - jamanetwork.com
Sepsis is medicine's last remaining preserve for unrestrainedantibioticprescribing.
TheSurvivingSepsisCampaign guidelines recommend empirical broadspectrum therapy …

Optimal antimicrobial therapy for sepsis

DN Fish - American journal of health-system pharmacy, 2002 - academic.oup.com
The selection of appropriate antimicrobial therapy for patients with sepsis is discussed.
Antimicrobial selection is based on the most likely source of infection, the most common …

Infectious Diseases Society of America position paper: recommended revisions to the national severe sepsis and septic shock early management bundle (SEP-1) …

C Rhee, K Chiotos, SE Cosgrove… - Clinical Infectious …, 2021 - academic.oup.com
Abstract The Centers for Medicare & Medicaid Services' Severe Sepsis and Septic Shock
Early Management Bundle (SEP-1) measure has appropriately established sepsis as a …

Empirical antimicrobial therapy of septic shock patients: adequacy and impact on the outcome

M Leone, A Bourgoin, S Cambon, M Dubuc… - Critical care …, 2003 - journals.lww.com
Empirical antimicrobial therapy of septic shock patients: Ad... : Critical Care Medicine Empirical
antimicrobial therapy of septic shock patients: Adequacy and impact on the outcome* : Critical …

The determinants of hospital mortality among patients with septic shock receiving appropriate initial antibiotic treatment

A Labelle, P Juang, R Reichley, S Micek… - Critical care …, 2012 - journals.lww.com
Objective: To identify the determinants of hospital mortality among patients with septic shock
receiving appropriate initial antibiotic treatment. Design: A retrospective cohort study of …

Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program

R Ferrer, I Martin-Loeches, G Phillips… - Critical care …, 2014 - journals.lww.com
Objectives: Compelling evidence has shown that aggressive resuscitation bundles,
adequate source control, appropriate antibiotic therapy, and organ support are cornerstone …