[PDF][PDF] Genotools SNP manager: a new software for automated high-throughput MALDI-TOF mass spectrometry SNP genotyping

W Pusch, KO Kraeuter, T Froehlich… - …, 2001 - pdfs.semanticscholar.org
Analysis of single nucleotide polymorphisms (SNPs) is a rapidly growing field of research
that provides insights into the most common type of differences between individual …

High‐throughput multiplex SNP genotyping with MALDI‐TOF mass spectrometry: practice, problems and promise

MS Bray, E Boerwinkle, PA Doris - Human mutation, 2001 - Wiley Online Library
Single nucleotide polymorphisms (SNPs) are currently being identified and mapped at a
remarkable pace, providing a rich genetic resource with vast potential for disease gene …

Genotyping single nucleotide polymorphisms by MALDI mass spectrometry in clinical applications

J Tost, IG Gut - Clinical biochemistry, 2005 - Elsevier
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry
has become one of the most powerful and widely applied technologies for SNP scoring and …

MALDI-TOF mass spectrometry-based SNP genotyping

W Pusch, JH Wurmbach, H Thiele… - …, 2002 - Taylor & Francis
In recent years a growing demand for simple and robust SNP genotyping platforms has
arisen from the widespread use of SNPs in industrial and public research. The resulting …

Single-nucleotide polymorphism analysis by MALDI–TOF mass spectrometry

TJ Griffin, LM Smith - Trends in biotechnology, 2000 - cell.com
Single-nucleotide polymorphisms (SNPs) have great potential for use in genetic-mapping
studies, which locate and characterize genes that are important in human disease and …

MALDI-TOF MS: a platform technology for genetic discovery

D van den Boom, M Beaulieu, P Oeth, R Roth… - International Journal of …, 2004 - Elsevier
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry
(MS) has been applied as a high-throughput platform technology for qualitative and …

DNA analysis by MALDI‐TOF mass spectrometry

IG Gut - Human mutation, 2004 - Wiley Online Library
The last decade has seen an increased demand for high‐throughput DNA analysis. This is
mainly due to the human genome sequencing project that is now completed. Matrix‐assisted …

Genotyping single-nucleotide polymorphisms by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry

S Sauer, IG Gut - Journal of Chromatography B, 2002 - Elsevier
In recent years matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
(MALDI) has emerged as a very powerful method for genotyping single nucleotide …

Quantitative approach to single-nucleotide polymorphism analysis using MALDI-TOF mass spectrometry

P Ross, L Hall, LA Haff - Biotechniques, 2000 - Taylor & Francis
Pooling of DNA samples before genotyping is a valuable means of streamlining large-scale
genotyping efforts in disease association studies, single-nucleotide polymorphism (SNP) …

Large-scale genotyping by mass spectrometry: experience, advances and obstacles

D Lechner, GM Lathrop, IG Gut - Current opinion in chemical biology, 2002 - Elsevier
Single nucleotide polymorphism (SNP) genotyping has become a key technology for genetic
studies. In recent years, matrix-assisted laser desorption/ionization (MALDI) time-of-flight …