Efficient secretion of a folded protein domain by a monomeric bacterial autotransporter

KM Skillman, TJ Barnard, JH Peterson… - Molecular …, 2005 - Wiley Online Library
Bacterial autotransporters are proteins that contain a small C‐terminal 'β domain'that
facilitates translocation of a large N‐terminal 'passenger domain'across the outer membrane …

Incorporation of a polypeptide segment into the β‐domain pore during the assembly of a bacterial autotransporter

R Ieva, KM Skillman, HD Bernstein - Molecular microbiology, 2008 - Wiley Online Library
Bacterial autotransporters consist of an N‐terminal 'passenger domain'that is transported
into the extracellular space by an unknown mechanism and a C‐terminal 'β‐domain'that …

Secretion of a bacterial virulence factor is driven by the folding of a C-terminal segment

JH Peterson, P Tian, R Ieva, N Dautin… - Proceedings of the …, 2010 - National Acad Sciences
Autotransporters are bacterial virulence factors consisting of an N-terminal “passenger
domain” that is secreted in a C-to-N-terminal direction and a C-terminal “β domain” that …

An unusual signal peptide facilitates late steps in the biogenesis of a bacterial autotransporter

RL Szabady, JH Peterson… - Proceedings of the …, 2005 - National Acad Sciences
Bacterial autotransporters are proteins that use a C-terminal porin-like domain to facilitate
the transport of an upstream “passenger domain” across the outer membrane. Although …

Cleavage of a bacterial autotransporter by an evolutionarily convergent autocatalytic mechanism

N Dautin, TJ Barnard, DE Anderson… - The EMBO journal, 2007 - embopress.org
Bacterial autotransporters are comprised of an N‐terminal 'passenger domain'and a C‐
terminal β barrel ('β domain') that facilitates transport of the passenger domain across the …

Autotransporter structure reveals intra-barrel cleavage followed by conformational changes

TJ Barnard, N Dautin, P Lukacik… - Nature structural & …, 2007 - nature.com
Autotransporters are virulence factors produced by Gram-negative bacteria. They consist of
two domains, an N-terminal'passenger'domain and a C-terminal β-domain. β-domains form …

Mechanistic link between β barrel assembly and the initiation of autotransporter secretion

O Pavlova, JH Peterson, R Ieva… - Proceedings of the …, 2013 - National Acad Sciences
Autotransporters are bacterial virulence factors that contain an N-terminal extracellular
(“passenger”) domain and a C-terminal β barrel (“β”) domain that anchors the protein to the …

Are bacterial 'autotransporters' really transporters?

HD Bernstein - Trends in microbiology, 2007 - cell.com
Autotransporters are bacterial outer membrane proteins that consist of a large N-terminal
extracellular domain ('passenger domain') and a C-terminal β-barrel domain ('β domain') …

Structure of the translocator domain of a bacterial autotransporter

CJ Oomen, P van Ulsen, P Van Gelder, M Feijen… - The EMBO …, 2004 - embopress.org
Autotransporters are virulence‐related proteins of Gram‐negative bacteria that are secreted
via an outer‐membrane‐based C‐terminal extension, the translocator domain. This domain …

[HTML][HTML] Reconstitution of bacterial autotransporter assembly using purified components

G Roman-Hernandez, JH Peterson, HD Bernstein - elife, 2014 - elifesciences.org
Autotransporters are a superfamily of bacterial virulence factors consisting of an N-terminal
extracellular ('passenger') domain and a C-terminal β barrel ('β') domain that resides in the …