Abstract The translocation (8; 21)(q22; q22) is commonly associated with acute myeloid
leukemia (AML) M2 according to the French‐American‐British (FAB) classification. We …

The translocation t (8; 21)(q22; q22) is found in 40% of cases of acute myeloid leukemia
(AML) designated as the subtype M2 in the French-American-British (FAB) classification …

The complex variants of t (8; 21) involving chromosomes 8 and 21 as well as a variable
chromosome account for 1.1∼ 5% of acute myeloid leukemia (AML) patients. This paper …

Studies of large numbers of patients have enabled the identification of relatively infrequent
chromosome changes, such as inv (3)(q21; q26), t (6; 9)(p23; q34) and t (8; 16)(p11; p11) …

A subgroup of patients with core binding factor acute myeloid leuke-mias (AML) is
characterized by the presence of the fusion gene CBFb-Myh11. At the cytogenetic level …

Translocation t (7; 11)(p15; p15) is an uncommon but recurrent chromosome aberration in
acute myeloid leukaemia (AML), which occurs mostly in oriental patients and in AML M2 or …

We report a patient with acute myeloid leukemia (AML) and t (3; 21; 8)(q21; q22; q22). This
translocation has not been previously described in de novo or relapsed AML. The patient is …

“Simple” variants of the t (8; 21) translocation involving chromosome 8 and a chromosome
other than number 21 are rare. To our knowledge, only t (3; 8)(q29; q22), t (8; 11)(q22; q13) …

Following reports of childhood acute myeloid leukemia (AML) showing that patients with t (9;
11)(p22; q23) have a better prognosis than those with translocations between 11q23 and …

Chromosome 21 and in particular band 21q22, the site of AML1 (RUNX1, CBFA2) gene, is
among the most frequent targets of chromosomal translocations in leukemia observed in …