Annexin A2/P11 interaction: new insights into annexin A2 tetramer structure by chemical crosslinking, high‐resolution mass spectrometry, and computational modeling

DM Schulz, S Kalkhof, A Schmidt… - Proteins: Structure …, 2007 - Wiley Online Library
During the past few years, the structural analysis of proteins and protein complexes by
chemical crosslinking and mass spectrometry has enjoyed increasing popularity. With this …

Crystal structures of sodium-bound annexin A4

K Butsushita, SI Fukuoka, K Ida… - Bioscience, biotechnology …, 2009 - Taylor & Francis
Annexin A4 (Anx4) possesses four repeat domains with one Ca2+-binding site (CBS) in
each domain. In this study, we resolved two crystal structures of the Na+-bound form at high …

Mapping of three unique Ca2+‐binding sites in human annexin II

M Jost, C Thiel, K Weber… - European journal of …, 1992 - Wiley Online Library
Site‐directed mutagenesis was employed to map and characterize Ca2+‐binding sites in
annexin II, a member of the annexin family of Ca2+–and phospholipid‐binding proteins …

[HTML][HTML] Annexin A2: the importance of being redox sensitive

PA Madureira, DM Waisman - International Journal of Molecular Sciences, 2013 - mdpi.com
Hydrogen peroxide (H2O2) is an important second messenger in cellular signal
transduction. H2O2-dependent signalling regulates many cellular processes, such as …

Annexin XII E105K crystal structure: identification of a pH-dependent switch for mutant hexamerization

JP Cartailler, HT Haigler, H Luecke - Biochemistry, 2000 - ACS Publications
Annexins are a family of calcium-and phospholipid-binding proteins involved with numerous
cellular processes including membrane fusion, ion channel activity, and heterocomplex …

Annexin A1, A2, A5, and A6 involvement in human pathologies

LP de Souza Ferreira, RA da Silva… - Proteins: Structure …, 2023 - Wiley Online Library
The human genome codes for 12 annexins with highly homologous membrane‐binding
cores and unique amino termini, which endow each protein with its specific biological …

Annexin VI interacts with adenine nucleotides and their analogs

M Danieluk, S Pikuła, J Bandorowicz-Pikuła - Biochimie, 1999 - Elsevier
Annexin VI (AnxVI), a member of the annexin family of Ca2+-and membrane-binding
proteins, has been shown to interact in vitro with adenine nucleotides. Furthermore, it has …

A novel annexin A2 protein with platelet aggregation-inhibiting activity from amphibian Bombina maxima skin

Y Zhang, G Yu, Y Wang, J Zhang, S Wei, W Lee… - Toxicon, 2010 - Elsevier
Annexin A2 is a unique member of annexin family with multi-functions in membrane
physiology, implicated in inflammation and cancer progression. mRNA of Annexin A2 is …

A putative consensus sequence for the nucleotide-binding site of annexin A6

J Bandorowicz-Pikula, A Kirilenko, R van Deursen… - Biochemistry, 2003 - ACS Publications
Reaction-induced infrared difference spectroscopy (RIDS) has been used to investigate the
nature of interactions of human annexin A6 (ANXA6) with nucleotides. RIDS results for …

Annexins sense changes in intracellular pH during hypoxia

K Monastyrskaya, F Tschumi, EB Babiychuk… - Biochemical …, 2008 - portlandpress.com
The pHi (intracellular pH) is an important physiological parameter which is altered during
hypoxia and ischaemia, pathological conditions accompanied by a dramatic decrease in …