[HTML][HTML] Critical role of FOXO3a in carcinogenesis

Y Liu, X Ao, W Ding, M Ponnusamy, W Wu, X Hao… - Molecular cancer, 2018 - Springer
FOXO3a is a member of the FOXO subfamily of forkhead transcription factors that mediate a
variety of cellular processes including apoptosis, proliferation, cell cycle progression, DNA …

Current perspective on the regulation of FOXO4 and its role in disease progression

W Liu, Y Li, B Luo - Cellular and Molecular Life Sciences, 2020 - Springer
Abstract Forkhead box O4 (FOXO4) is a member of the FOXO family that regulates a number
of genes involved in metabolism, cell cycle, apoptosis, and cellular homeostasis via …

[HTML][HTML] FoxO3a and disease progression

RS Nho, P Hergert - World journal of biological chemistry, 2014 - ncbi.nlm.nih.gov
Abstract The Forkhead box O (FoxO) family has recently been highlighted as an important
transcriptional regulator of crucial proteins associated with the many diverse functions of …

FOXO1: a potential target for human diseases

H Lu, H Huang - Current drug targets, 2011 - ingentaconnect.com
The forkhead box O (FoxO) transcription factors are known to be involved in many
physiological and pathological processes including apoptosis, cell cycle arrest, stress …

FOXO transcription factors in cancer development and therapy

A Coomans de Brachène, JB Demoulin - Cellular and molecular life …, 2016 - Springer
The forkhead box O (FOXO) transcription factors are considered as tumor suppressors that
limit cell proliferation and induce apoptosis. FOXO gene alterations have been described in …

FOXO factors: a matter of life and death

H Huang, DJ Tindall - 2006 - Future Medicine
Forkhead box O-class (FOXO) transcription factors, including FOXO1, FOXO3a and FOXO4,
function as tumor-suppressor proteins by inhibiting cell proliferation, promoting apoptotic cell …

FOX (M1) news—it is cancer

M Halasi, AL Gartel - Molecular cancer therapeutics, 2013 - AACR
FOXM1 is an oncogenic transcription factor of the Forkhead family and it has a well-defined
role in cell proliferation and cell-cycle progression. Expression of FOXM1 is excluded in …

FoxO family members in cancer

Y Zhang, B Gan, D Liu, J Paik - Cancer biology & therapy, 2011 - Taylor & Francis
The PI3K-Akt-FoxO signaling pathway plays a central role in diverse physiological
processes including cellular energy storage, growth, and survival, among others. As an …

[HTML][HTML] Regulation of FOXO protein stability via ubiquitination and proteasome degradation

H Huang, DJ Tindall - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2011 - Elsevier
Forkhead box O-class (FOXO) proteins are evolutionally conserved transcription factors.
They belong to a family of proteins consisting of FOXO1, FOXO3a, FOXO4 and FOXO6 in …

FOXO transcription factors: key regulators of cell fate

EWF Lam, RE Francis, M Petkovic - 2006 - portlandpress.com
FOXO (forkhead box O) transcription factors are crucial regulators of cell fate. This function of
FOXO proteins relies on their ability to control diverse and at times, opposing cellular …