The function and clinical application of extracellular vesicles in innate immune regulation

X Zhou, F Xie, L Wang, L Zhang, S Zhang… - Cellular & molecular …, 2020 - nature.com
The innate immune system plays a crucial role in the host defense against viral and
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …

The distinct roles of exosomes in innate immune responses and therapeutic applications in cancer

J Rezaie, T Etemadi, M Feghhi - European journal of pharmacology, 2022 - Elsevier
The innate immune system is one of the major constituents of the host's defense against
invading pathogens and extracellular vesicles (EVs) are involved in regulating its …

New insights into the biological impacts of immune cell-derived exosomes within the tumor environment

M Shen, X Ren - Cancer letters, 2018 - Elsevier
Exosomes are a group of nano-sized membrane vesicles that transfer proteins, nucleic
acids, and lipids to nearby and faraway cells, playing an important role in the intercellular …

Cancer-derived exosomes as effectors of key inflammation-related players

N Othman, R Jamal, N Abu - Frontiers in immunology, 2019 - frontiersin.org
Exosomes, a category of small lipid bilayer extracellular vesicles that are naturally secreted
by many cells (both healthy and diseased), carry cargo made up of proteins, lipids, DNAs …

Immune cell-derived exosomes in the cancer-immunity cycle

W Yan, S Jiang - Trends in cancer, 2020 - cell.com
Cells can communicate through extracellular vesicle (EV) secretion and uptake. Exosomes
are lipid bilayer-enclosed EVs of 30–150 nm in diameter, which can transfer RNA, functional …

The exosomes in tumor immunity

Y Liu, Y Gu, X Cao - Oncoimmunology, 2015 - Taylor & Francis
Exosomes are a kind of nanometric membrane vesicles and can be released by almost all
kinds of cells, including cancer cells. As the important mediators in intercellular …

Exosomes: versatile nano mediators of immune regulation

Q Li, H Wang, H Peng, T Huyan, NA Cacalano - Cancers, 2019 - mdpi.com
One of many types of extracellular vesicles (EVs), exosomes are nanovesicle structures that
are released by almost all living cells that can perform a wide range of critical biological …

Exosomes and immune response in cancer: friends or foes?

FM Barros, F Carneiro, JC Machado… - Frontiers in …, 2018 - frontiersin.org
Exosomes are a type of extracellular vesicle whose study has grown exponentially in recent
years. This led to the understanding that these structures, far from being inert waste by …

Extracellular vesicles in cancer immune microenvironment and cancer immunotherapy

F Xie, X Zhou, M Fang, H Li, P Su, Y Tu… - Advanced …, 2019 - Wiley Online Library
Extracellular vesicles (EVs) are secreted by almost all cells. They contain proteins, lipids,
and nucleic acids which are delivered from the parent cells to the recipient cells. Thereby …

Exosomes, their biogenesis and role in inter-cellular communication, tumor microenvironment and cancer immunotherapy

KK Jella, TH Nasti, Z Li, SR Malla, ZS Buchwald… - Vaccines, 2018 - mdpi.com
Exosomes are extracellular vesicles ranging from 30 to 150 nm in diameter that contain
molecular constituents of their host cells. They are released from different types of cells …