This study examines the extent to which memory CD4+ T cells share immunosurveillance
strategies with CD8+ resident memory T cells (T RM). After acute viral infection, memory …

We have previously demonstrated that mucosal CD4+ T cells expressing high levels of IL-7
receptor (IL-7Rhigh) are pathogenic cells responsible for chronic colitis. Here we investigate …

We report that oral infection with Yersinia pseudotuberculosis results in the development of
two distinct populations of pathogen-specific CD8+ tissue-resident memory T cells (TRM …

Mucosal tissues are continually bombarded with infectious agents seeking to gain entry into
the body. The absence of a tough physical exterior layer surrounding these tissues creates a …

Studies in mice and humans have shown that CD8+ T cell immunosurveillance in non-
lymphoid tissues is dominated by resident populations. Whether CD4+ T cells use the same …

Our knowledge about the kinetics and dynamics of complex pathogen‐specific CD8+ T cell
responses and the in vivo development of CD8+ memory T cells has increased substantially …

The oral mucosa is a critical barrier tissue that harbors a series of distinct immune cell
subsets. Immune surveillance in the oral mucosa is important for both local and systemic …

Intestinal dendritic cells (DCs) play key roles in mediating tolerance to commensal flora and
inflammatory responses against mucosal pathogens. The mechanisms by which intestinal …

To understand the perpetuation of inflammatory bowel disease (IBD), it is important to clarify
whether the colitogenic CD4+ T cells are self-limited effector or long-lived memory T cells …

Tissue-resident memory T cells (TRM cells) are a novel population of tissue-restricted
antigen-specific T cells. TRM cells are induced by pathogens and promote host defense …