Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways
S Chen, Y Li, B Chu, L Yuan, N Liu, Y Zhu, J Wang - Microorganisms, 2021 - mdpi.com
Salmonella Typhimurium (S. Typhimurium) is an aggressive zoonotic pathogen that causes
enteritis and diarrhea. Antibiotic therapy is still the primary method at present. However, the …
enteritis and diarrhea. Antibiotic therapy is still the primary method at present. However, the …
[HTML][HTML] NLRP3 inflammasome pathway has a critical role in the host immunity against clinically relevant Acinetobacter baumannii pulmonary infection
N Dikshit, SD Kale, HJ Khameneh, V Balamuralidhar… - Mucosal …, 2018 - Elsevier
The opportunistic Gram-negative bacterium Acinetobacter baumannii (AB) is a leading
cause of life-threatening nosocomial pneumonia. Outbreaks of multidrug resistant (MDR)-AB …
cause of life-threatening nosocomial pneumonia. Outbreaks of multidrug resistant (MDR)-AB …
Vibrio alginolyticus Triggers Inflammatory Response in Mouse Peritoneal Macrophages via Activation of NLRP3 Inflammasome
J Wang, Q Ding, Q Yang, H Fan, G Yu, F Liu… - Frontiers in Cellular …, 2021 - frontiersin.org
Vibrio alginolyticus is a food-borne marine Vibrio that causes gastroenteritis, otitis media,
otitis externa, and septicemia in humans. The pathogenic mechanisms of V. alginolyticus …
otitis externa, and septicemia in humans. The pathogenic mechanisms of V. alginolyticus …
Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy
The nucleotide-binding domain, leucine-rich repeat containing family caspase recruitment
domain containing 4 (NLRC4) inflammasome can be activated by pathogenic bacteria via …
domain containing 4 (NLRC4) inflammasome can be activated by pathogenic bacteria via …
Role of inflammasomes in host defense against Citrobacter rodentium infection
Citrobacter rodentium is an enteric bacterial pathogen of the mouse intestinal tract that
triggers inflammatory responses resembling those of humans infected with …
triggers inflammatory responses resembling those of humans infected with …
Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo
Y Chen, R Li, Z Wang, X Hou, C Wang, Y Ai, W Shi… - Cellular …, 2020 - Elsevier
Uncontrolled activation of NLRP3 inflammasome initiates a series of human inflammatory
diseases. Targeting NLRP3 inflammasome has attracted considerable attention in …
diseases. Targeting NLRP3 inflammasome has attracted considerable attention in …
Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-κB signaling
Vibrio vulnificus and Vibrio cholerae are Gram-negative pathogens that cause serious
infectious disease in humans. The β form of pro–IL-1 is thought to be involved in …
infectious disease in humans. The β form of pro–IL-1 is thought to be involved in …
Cinnamaldehyde inhibits the NLRP3 inflammasome by preserving mitochondrial integrity and augmenting autophagy in Shigella sonnei-infected macrophages
KF Hua, YB Lin, HW Chiu, WT Wong, SM Ka… - Journal of …, 2024 - Springer
Background Worldwide, more than 125 million people are infected with Shigella each year
and develop shigellosis. In our previous study, we provided evidence that Shigella sonnei …
and develop shigellosis. In our previous study, we provided evidence that Shigella sonnei …
[HTML][HTML] The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge
KW Chen, CJ Groß, FV Sotomayor, KJ Stacey… - Cell reports, 2014 - cell.com
The macrophage NLRC4 inflammasome drives potent innate immune responses against
Salmonella by eliciting caspase-1-dependent proinflammatory cytokine production (eg …
Salmonella by eliciting caspase-1-dependent proinflammatory cytokine production (eg …
Endoplasmic Reticulum Stress Mediated NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Macrophages Infected with Bacillus Calmette-Guérin
X Nie, B Ma, L Liu, X Yuan, M Li, Y Liu, Y Hou… - International Journal of …, 2023 - mdpi.com
Tuberculosis (TB) is a zoonotic infectious disease caused by Mycobacterium tuberculosis
(Mtb). Mtb is a typical intracellular parasite, and macrophages are its main host cells. NLRP3 …
(Mtb). Mtb is a typical intracellular parasite, and macrophages are its main host cells. NLRP3 …