Aubipyc, ie [(bipydmb-H) Au (OH)][PF6](where bipydmb-H= deprotonated 6-(1, 1-
dimethylbenzyl)-2, 2′-bipyridine), Auoxo6, ie [(bipy2Me) 2Au2 (μ-O) 2][PF6] 2 (where …

In the last few years gold (III) complexes have attracted growing attention in the medicinal
chemistry community as candidate anticancer agents. In particular some organogold (III) …

Six homologous gold (III) dinuclear oxo-bridged complexes, of the type [(bipy nR) Au (µ-O) 2
Au (bipy nR)][PF 6] 2, bearing variously substituted 2, 2'-bipyridine ligands (bipy nR= 2, 2' …

The thioredoxin system plays a key role in regulating the overall intracellular redox balance.
It basically comprises the small redox protein thioredoxin (Trx), nicotinamide adenine …

Nowadays, gold compounds constitute a family of very promising experimental agents for
cancer treatment. Indeed, several gold (I) and gold (III) compounds were shown to manifest …

Gold (III) compounds generally exhibit significant cytotoxic effects on cancer cell lines and
are of potential interest as antitumor drugs. We report here on the solution chemistry, the …

Gold compounds form an attractive class of cytotoxic metal compounds of potential
application as anticancer agents. Notably, the mode of action of cytotoxic gold compounds …

Two dinuclear oxo-bridged organogold (iii) compounds, namely [(N, N, C) 2Au2 (μ-O)][PF6]
2 (with N, N, CH= 6-(1-methylbenzyl)-2, 2′-bipyridine, Au22O1; or 6-(1, 1-dimethylbenzyl) …

A series of six dinuclear gold (III) oxo complexes with bipyridyl ligands, of general formula
[Au2 (N, N) 2 (μ-O) 2][PF6] 2 (Auoxo1− Auoxo6)[where N, N= 2, 2 '-bipyridine (1), 4, 4 '-di-tert …

We have recently shown that a group of structurally diverse gold compounds are highly
cytotoxic toward a panel of 36 human tumor cell lines through a variety of biochemical …