Cardiovascular outcomes trials for weight loss interventions: another tool for cardiovascular prevention?

IJ Neeland, DK McGuire, N Sattar - Circulation, 2021 - Am Heart Assoc
With the development of newer weight loss agents with more marked effects on body weight,
in some instances approaching the weight-loss effects of bariatric surgery, we may soon …

Obesity and Cardiovascular Disease: A New Dawn

N Sattar, IJ Neeland, DK McGuire - Circulation, 2024 - Am Heart Assoc
The recently reported SELECT trial (Semaglutide Effects on Heart Disease and Stroke in
Patients With Overweight or Obesity) 3 tested this hypothesis using the higher-dose …

SELECT semaglutide to improve outcomes in patients with obesity and cardiovascular disease, also without diabetes

G Gajos - Cardiology Journal, 2024 - journals.viamedica.pl
More than half the world population is expected to be overweight or obese by the year 2035
[1]. Obesity and atherosclerotic cardiovascular disease have always been a fatal …

Glucagon-like peptide-1 receptor agonists: the key to healthy weight loss maintenance?

EW Lehmann, SS Torekov - Cardiovascular Research, 2021 - academic.oup.com
Obesity is a chronic condition associated with a range of comorbidities, physical inactivity,
and decreased quality of life. Disturbingly, the prevalence continues to escalate, children …

Cardiovascular outcome trials in obesity: a review

JPH Wilding, S Jacob - Obesity reviews, 2021 - Wiley Online Library
Obesity is a global epidemic associated with over 200 health complications and a significant
risk of developing cardiovascular disease (CVD), partly by increasing classical risk factors …

The SELECT trial of semaglutide in patients with overweight or obesity without diabetes: establishing a new pathway to secondary prevention of cardiovascular …

AM Lincoff, DH Ryan - 2024 - academic.oup.com
Overweight or obesity has been independently associated with increased cardiovascular
risk, yet interventional trials of lifestyle or pharmacologic management strategies for …

Reducing cardiovascular outcomes with semaglutide: a metabolic route for a SELECT few

G Liuzzo, C Patrono - 2024 - academic.oup.com
• In the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or
Obesity trial, the SELECT Investigators tested the hypothesis that the addition of …

From the Editors: New concepts in obesity and cardiovascular disease

PB Duell, KC Maki - Journal of clinical lipidology, 2023 - lipidjournal.com
Progress in the field of obesity may seem to have progressed at a snail's pace, but
tremendous advances have been made during the last few decades in our understanding of …

SELECT shows cardiovascular risk reduction with weight-loss drug semaglutide in people without diabetes

I Fernández-Ruiz - Nature Reviews Cardiology, 2024 - nature.com
Treatment with the glucagon-like peptide 1 receptor agonist semaglutide, administered
subcutaneously at a dose of 2.4 mg once per week, reduces the risk of major cardiovascular …

[HTML][HTML] Prioritizing obesity treatment: expanding the role of cardiologists to improve cardiovascular health and outcomes

DH Ryan, JE Deanfield, S Jacob - … Endocrinology & Metabolism, 2023 - journals.lww.com
Obesity is a major risk factor for cardiovascular disease, yet management remains poor.
Cardiologists and healthcare professionals treating people with high cardiovascular risk are …