Changes in γδT cells in peripheral blood of patients with ulcerative colitis exacerbations

A Gryglewski, P Richter, M Szczepanik - Archivum Immunologiae et …, 2021 - Springer
The role of γδT cells in ulcerative colitis (UC) is well confirmed in experimental animals and
demonstrated in many clinical observations. Recent investigations have indicated that UC is …

Tumor‐Activated TCRγδ+ T Cells from Gastric Cancer Patients Induce the Antitumor Immune Response of TCRαβ+ T Cells via Their Antigen‐Presenting Cell‐Like …

C Mao, X Mou, Y Zhou, G Yuan, C Xu… - Journal of …, 2014 - Wiley Online Library
Human γδ T cells display the principal characteristics of professional antigen‐presenting
cells (APCs), in addition to playing a vital role in immunity through cytokine secretion and …

ANALYSIS OF CD8+CD28 T-SUPPRESSOR CELLS IN GASTRIC CANCER PATIENTS

Y Shen, QX Qu, YB Zhu, XG Zhang - Journal of Immunoassay and …, 2012 - Taylor & Francis
Host anti-tumor immune responses can be attenuated by suppressor T cells of the
phenotype CD8+ CD28−(Ts cells). In the present study, we investigated the presence of …

Low counts of γδ T cells in peritumoral liver tissue are related to more frequent recurrence in patients with hepatocellular carcinoma after curative resection

XY Cai, JX Wang, Y Yi, HW He, XC Ni… - Asian Pacific Journal …, 2014 - koreascience.kr
Objectives: TCR-gamma-delta+ T cells (${\gamma}{\delta} $ T cells) are non-conventional T
lymphocytes that can recognize and eradicate tumor cells. Our previous studies showed that …

Gut γδ T cells as guardians, disruptors, and instigators of cancer

T Suzuki, L Hayman, A Kilbey, J Edwards… - Immunological …, 2020 - Wiley Online Library
Colorectal cancer is the third most common cancer worldwide with nearly 2 million cases per
year. Immune cells and inflammation are a critical component of colorectal cancer …

Characterisation of γδ T cells in renal cell carcinoma patients by polymerase chain reaction analysis of T cell receptor transcripts

C Olive, D Nicol, MC Falk - Cancer Immunology, Immunotherapy, 1997 - Springer
Renal cell carcinomas (RCC) contain tumour infiltrating lymphocytes (TIL) but these are
essentially immunosuppressed in that they do not generate effective antitumour immune …

Tumor-infiltrating γδ T lymphocytes: pathogenic role, clinical significance, and differential programing in the tumor microenvironment

E Lo Presti, F Dieli, S Meraviglia - Frontiers in immunology, 2014 - frontiersin.org
There is increasing clinical evidence indicating that the immune system may either promote
or inhibit tumor progression. Several studies have demonstrated that tumors undergoing …

Lymphocytes infiltrating normal human lung and lung carcinomas rarely express γδ T cell antigen receptors

I Fajac, A Tazi, AJ Hance, F Bouchonnet… - Clinical & …, 1992 - academic.oup.com
It has been suggested that T lymphocytes expressing γδ T cell receptors (TCR) could play
an important role in the defence of epithelia against infection and neoplastic transformation …

CD3+ CD56+ CD8+ cells demonstrating a suppressor T cell-like function in the peripheral blood of colon cancer patients

J Akagi, E Takai, Y Tamori… - … journal of oncology, 2001 - spandidos-publications.com
We previously reported that HLA-unrestricted CTLs against MUC-1 were induced from colon
cancer patients by stimulating peripheral blood lymphocytes (PBLs) with recombinant MUC …

Characterization of double-negative T cells in colorectal cancers and their corresponding lymph nodes

K Okamura, L Wang, S Nagayama, M Yamashita… - …, 2024 - Taylor & Francis
ABSTRACT TCRαβ+ CD4− CD8− double-negative T (DNT) cells are minor populations in
peripheral blood, and their roles have mostly been discussed in inflammation and …