The triple-helical structure of collagen peptides has recently been harnessed as a subunit in
the higher-order assembly of unique biomaterials. Specific assembly signals have been …

We have designed, synthesized, and characterized a short (32-mer; 8-nm), single-stranded,
collagen-related peptide (CRP), 1a, which forms triple-helical building blocks that self …

Self-assembling peptides have become an important subclass of next-generation
biomaterials. In particular, materials that mimic the properties of collagen have received …

We report the design of two collagen-mimetic peptide sequences, NSI and NSII, that self-
assemble into structurally defined nanoscale sheets. The underlying structure of these …

Highlights•Collagen mimetic peptide biomaterials are superior to natural collagen in many
ways.•Strategic sequence design allows for reliable higher-order self-assembly.•Varying pH …

Synthetic collagen mimetic peptides are used to probe the role of hydrophobic forces in
mediating protein self-assembly. Higher order association is an integral property of natural …

Replicating the multi-hierarchical self-assembly of collagen has long-attracted scientists,
from both the perspective of the fundamental science of supramolecular chemistry and that …

Traditionally, collagen mimetic peptides (CMPs) have been used for elucidating the structure
of the collagen triple helix and the factors responsible for its stabilization. The wealth of …

The ability to recapitulate the features of natural collagen at the micro-and nanoscale with
novel biopolymers has the potential to lead to improved biomaterials. Herein we describe …

Metal ion‐mediated assembly of peptides is an intriguing method for developing novel
biomaterials. In particular, peptide building blocks based on collagen triple helical and …