TDP-43 (TAR DNA-binding protein 43) inclusions are a hallmark of amyotrophic lateral
sclerosis (ALS). In this study, we report that TDP-43 and nuclear factor κB (NF-κB) p65 …

TAR DNA-binding protein 43 (TDP-43) is a major component in aggregates of ubiquitinated
proteins in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration …

Transactive response DNA-binding protein-43 (TDP-43) is a multifunctional nucleic acid
binding protein present in ubiquitinated inclusions in tissues of patients with amyotrophic …

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are
characterized by cytoplasmic protein aggregates in the brain and spinal cord that include …

Introduction Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive
neurodegenerative disorder, and cytoplasmic inclusions containing transactive response …

The abnormal mislocalisation and ubiquitinated protein aggregation of the TAR DNA
binding protein 43 (TDP-43) within the cytoplasm of neurons and glia in the central nervous …

The cytoplasmic aggregation of TAR DNA binding protein-43 (TDP-43), also known as TDP-
43 pathology, is the pathological hallmark of amyotrophic lateral sclerosis (ALS). However …

Mutations in TAR DNA-binding protein 43 (TDP-43) are associated with familial forms of
amyotrophic lateral sclerosis (ALS), while wild-type TDP-43 is a pathological hallmark of …

TAR DNA-binding protein-43 (TDP-43) is a nuclear RNA-binding protein involved in many
cellular pathways. TDP-43-positive inclusions are a hallmark of amyotrophic lateral sclerosis …

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease that causes motor neuron
degeneration, progressive motor dysfunction, paralysis, and death. Although multiple …