Background: This report presents updated National Academy of Clinical Biochemistry
Laboratory Medicine Practice Guidelines summarizing quality requirements for the use of …

The National Academy of Clinical Biochemistry (NACB) Laboratory Medicine Practice
Guidelines for Use of Tumor Markers are intended to encourage more appropriate use of …

Increasing interest in the use of tumor markers in the clinical management of cancer patients
has encouraged development of guidelines by local, national and international groups …

We present here for comment and constructive critical appraisal the first draft of the new
NACB Guidelines on the use of Tumor Markers in the clinic. The preparation of these draft …

Background: Increasing interest in implementing the practice of evidence-based medicine in
oncology has encouraged the development of clinical guidelines, many of which include …

Tumor markers provide a minimally invasive, cost-effective source of data valuable for
monitoring disease course, determining prognosis, and aiding in treatment planning. An …

Clinical management decisions for patients with cancer are increasingly being guided by
prognostic and predictive markers. Use of these markers should be based on a sufficiently …

BACKGROUND The mission of the National Cancer Institute's Early Detection Research
Network (EDRN) is to identify and validate cancer biomarkers for clinical use. Since its …

A very broad definition of a tumor marker is: a tool that enables the clinician to answer
clinically relevant questions regarding a cancer disease (1). However, most researchers in …

Research methods for biomarker evaluation lag behind those for evaluating therapeutic
treatments. Although a phased approach to development of biomarkers exists and …