All pathology residents must have a good command of clinical chemistry, toxicology,
immunology, and laboratory statistics to be successful pathologists, as well as to pass the …

The last decade has seen an extraordinary amount of effort devoted in biomedical research
to the field of biomarkers. There have been some notable successes with novel markers …

Increasing numbers of commercial assays for the established tumour markers are available
which are capable of excellent analytical performance. Whilst all these assays are useful as …

Background The introduction of new biomarkers can lead to inappropriate utilization of tests
if they do not fill in existing gaps in clinical care. We aimed to define a strategy and checklist …

This article describes the principles of marker research with prospective studies along with
examples for diagnostic tumor markers. A plethora of biomarkers have been claimed as …

Screening for premalignant lesions or early invasive disease has the potential to reduce
mortality from cancer. Because of their ease of measurement, several biomarkers have been …

The biomarker pipeline to develop and evaluate cancer screening tests has three stages:
identification of promising biomarkers for the early detection of cancer, initial evaluation of …

Advances in genomic and proteomic profiling of disease have transformed the field of
molecular diagnostics, thus leading the way for a major revolution in clinical practice. While …

As a part of ongoing efforts of the NCI-FDA Interagency Oncology Task Force subcommittee
on molecular diagnostics, members of the Clinical Proteomic Technology Assessment for …

Serum determinations of tumor markers are indispensable in the diagnosis and
management of cancer, and therefore play an important role in clinical practice. After a short …