Ginsenoside‐Rd attenuates oxidative damage related to aging in senescence‐accelerated mice

T Yokozawa, A Satoh, EJ Cho - Journal of pharmacy and …, 2004 - Wiley Online Library
Among the various theories of the aging process, the free radical theory, which proposes
that deleterious actions of free radicals are responsible for the functional deterioration …

Protective effects of ginsenoside Rg1 on splenocytes and thymocytes in an aging rat model induced by d-galactose

J Sun, L Zhang, J Zhang, R Ran, Y Shao, J Li… - International …, 2018 - Elsevier
Physiological aging is associated with a range of medical problems. However, the treatment
of aging-associated diseases and prolonging human life are vital to our current aging …

Panax ginseng reduces oxidative stress and restores antioxidant capacity in aged rats

T Ramesh, SW Kim, SY Hwang, SH Sohn, SK Yoo… - Nutrition research, 2012 - Elsevier
Nutritional antioxidants interact with cells in an active mode, including retrieving and sparing
one another, to diminish oxidative stress. However, the intracellular balance of prooxidants …

Long-term ginsenoside administration prevents memory loss in aged female C57BL/6J mice by modulating the redox status and up-regulating the plasticity-related …

HF Zhao, Q Li, Y Li - Neuroscience, 2011 - Elsevier
Memory impairment is considered to be one of the most prominent consequences of aging.
Deterioration of memory begins in advance of old age in animals, including humans. The …

Effect of fermented Panax ginseng extract (GINST) on oxidative stress and antioxidant activities in major organs of aged rats

T Ramesh, SW Kim, JH Sung, SY Hwang… - Experimental …, 2012 - Elsevier
The intracellular levels of oxidant and antioxidant balances are gradually distorted during
the aging process. An age associated elevation of oxidative stress occurring throughout the …

Ginsenoside Rg1 delays tert-butyl hydroperoxide-induced premature senescence in human WI-38 diploid fibroblast cells

X Chen, J Zhang, Y Fang, C Zhao… - The Journals of …, 2008 - academic.oup.com
Tert-butyl hydroperoxide (t-BHP), an analog of hydroperoxide, induced characteristic
changes of senescence in human diploid fibroblasts WI-38 cells. It was reported that …

Antioxidative effects related to the potential anti-aging properties of the Chinese prescription Kangen-karyu and Carthami Flos in senescence-accelerated mice

A Satoh, T Yokozawa, EJ Cho, T Okamoto… - Archives of gerontology …, 2004 - Elsevier
The popular oxidative stress theory predicts that enhancement of the antioxidative defense
system to attenuate free radical-induced damage counteracts the aging process. We used …

Ginsenoside Rb1 retards aging process by regulating cell cycle, apoptotic pathway and metabolism of aging mice

S Yu, H Xia, Y Guo, X Qian, X Zou, H Yang… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Ginsenoside Rb1 (GRb1), an active ingredient of
traditional Chinese medicine Panax ginseng CA Meyer, has displayed various activities …

The anti-aging mechanism of ginsenosides with medicine and food homology

T Tian, CN Ko, W Luo, D Li, C Yang - Food & Function, 2023 - pubs.rsc.org
With the acceleration of global aging and the rise in living standards, the achievement of
healthy aging is becoming an imperative issue globally. Ginseng, a medicinal plant that has …

Neuroprotective effects of pretreatment of ginsenoside R b1 on severe cerebral ischemia‐induced injuries in aged mice: Involvement of anti‐oxidant signaling

X Dong, L Zheng, S Lu, Y Yang - Geriatrics & Gerontology …, 2017 - Wiley Online Library
Aim Ginsenosides, a class of ginseng compounds of herbal medicine, have been shown to
have therapeutic potential for the neuroprotection of brain damage after cerebral ischemia …