Resistance to the polycationic antibiotic polymyxin B and expression of the outer-membrane
protein OprH in the opportunistic pathogen Pseudomonas aeruginosa both involve the PhoP …

Rapid adaptation to environmental challenge is essential for the survival of many bacterial
species, and is often effectively mediated by two‐component regulatory systems. Part of the …

The two‐component regulatory system PhoP‐PhoQ of Pseudomonas aeruginosa regulates
resistance to cationic antimicrobial peptides, polymyxin B and aminoglycosides in response …

Overexpression of major outer membrane protein OprH of Pseudomonas aeruginosa as a
result of mutation (in strain H181) or adaptation to low Mg2+ concentrations (in parent strain …

The cloned oprH gene of Pseudomonas aeruginosa was mutated by inserting a 1.4-kbp
fragment that encodes tetracycline resistance. This mutated gene was then incorporated into …

Pseudomonas aeruginosa, a gram-negative bacterium of human pathogens, is noted for its
environmental versatility, enormous metabolic capacity, and resistance to antibiotics …

When grown in divalent cation-limited medium, Pseudomonas aeruginosa becomes
resistant to cationic antimicrobial peptides and polymyxin B. This resistance is regulated by …

Pseudomonas aeruginosa can develop resistance to polymyxin as a consequence of
mutations in the PhoPQ regulatory system, mediated by covalent lipid A modification …

The adaptation of Pseudomonas aeruginosa to its environment, including the host, is tightly
controlled by its network of regulatory systems. The two-component regulatory system …

Constitutive overexpression of the active efflux system MexXY/OprM is a major cause of
resistance to aminoglycosides, fluoroquinolones, and cefepime in clinical strains of …