Neuromyelitis optica (NMO) is a severe inflammatory CNS disorder of putative autoimmune
aetiology, which predominantly affects the spinal cord and optic nerves. Recently, a highly …

Background Neuromyelitis optica (NMO) is a demyelinating disease of the central nervous
system (CNS) of putative autoimmune aetiology. Early discrimination between multiple …

Antibodies to aquaporin-4 (also known as AQP4-Ab or NMO-IgG) are sensitive and highly
specific serum markers of autoimmune neuromyelitis optica (NMO). Second-generation …

Neuromyelitis optica (NMO) is a severe, debilitating human disease that predominantly
features immunopathology in the optic nerves and the spinal cord. An IgG1 autoantibody …

Neuromyelitis optica (NMO) is an inflammatory and necrotizing disease clinically
characterized by selective involvement of the optic nerves and spinal cord. There has been …

Abstract Background In 70-80% of cases, neuromyelitis optica (NMO) is associated with
highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG) …

Background Neuromyelitis optica (NMO), a severe demyelinating disease, represents itself
with optic neuritis and longitudinally extensive transverse myelitis. Serum NMO-IgG …

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that typically affects
optic nerves and spinal cord. Its pathogenic relationship to multiple sclerosis (MS) is …

Neuromyelitis optica (NMO) is a rare CNS inflammatory disorder that predominantly affects
the optic nerves and spinal cord. Recent serological findings strongly suggest that NMO is a …

Abstract Aquaporin‐4 (AQP 4) is a water channel protein that is most highly, but not
exclusively, expressed in the central nervous system. In 2005 AQP 4 was shown to be the …