Approximately 1 in 6 couples in the Western world is not able to conceive spontaneously
after 1 year of unprotected intercourse; in nearly half of these couples, the male partner has …

Male infertility is an extraordinarily common problem affecting 1 in 25 men. Despite active
research, the underlying causal factors remain unknown in a large percentage (40%) of …

Male infertility is a common and complex disease, manifesting as a wide range of
phenotypes, ranging from apparently normal semen parameters with an inexplicable …

A thorough understanding of the genetic basis of male infertility has eluded researchers in
spite of significant efforts to identify novel genetic causes of the disease, particularly over the …

Male infertility is a common and severe health problem. Infertility not only affects one's ability
to have children, but also has emotional, psychological, family, and societal effects. Despite …

Developments in genomic medicine will likely explain much of what is now considered
idiopathic male infertility. Indeed, our understanding of the genetic defects that cause …

Purpose: Greater than 10% of couples are unable to achieve pregnancy. In at least 30% to
50% of these infertility cases a male factor abnormality is involved. Genetic defects are …

Early in embryogenesis, cells that are destined to become germ cells take on a different
destiny from other cells in the embryo. The germ cells are not programmed to perform “vital” …

Understanding the genetic basis of idiopathic male infertility has long been the focus of
many researchers. Numerous recent studies have attempted to identify relevant single …

While 7% of the men are infertile, currently, a genetic etiology is identified in less than 25%
of those men, and 30% of the infertile men lack a definitive diagnosis, falling in the …