Neuroblastoma (NB) is the most common and deadliest extracranial solid tumor in children.
Targeting tumor-associated macrophages (TAMs) is a strategy for attenuating tumor …

Background Glioma is the most common and lethal type of brain tumor, and it is
characterized by unfavorable prognosis and high recurrence rates. The reprogramming of …

Background: Hexokinase 3 (HK3) is one of the key enzymes involved in glucose
phosphorylation (the first step in most glucose metabolic pathways). Many studies have …

Abstract Background Hexokinase 2 (HK2) is an enzyme that catalyses the conversion of
glucose to glucose-6-phosphate, which has been found to be associated with malignant …

Background Glioma is the main subtype of primary central nervous system (CNS) tumor with
high malignancy and poor prognosis under current therapeutic approaches. Glycolysis and …

Abstract Hexokinase 2 (HK2) has been associated with carcinogenic growth in numerous
kinds of malignancies as essential regulators during the processing of glucose. This study …

Tumor-associated macrophages (TAMs) play an important role in the immune response to
cancer, but the mechanisms by which the tumor microenvironment controls TAMs and T cell …

In our previous perspective, we investigated the role of hypoxic lesions in the development
of necrotic zone in solid tumors (1). We suggested the increased infiltration of macrophages …

A number of biomarkers have been identified for various cancers. However, biomarkers
associated with glioma remain largely to be explored. In the current study, we investigated …

JNK activity has been implicated in the malignant proliferation, invasion and drug‐resistance
of glioma cells (GCs), but the molecular mechanisms underlying JNK activation are currently …