Introduction The UK's current National Institute for Health and Care Excellence and the
American Psychiatric Association's depression guidelines state that withdrawal reactions …

Withdrawal reactions when coming off antidepressants have long been neglected or
minimised. It took almost two decades after the selective serotonin reuptake inhibitors …

We now recognise that withdrawal symptoms from antidepressants are common, and can be
severe and long-lasting in some people. Many withdrawal symptoms overlap with symptoms …

Background: Stopping antidepressants commonly causes withdrawal symptoms, which can
be severe and long-lasting. National Institute for Health and Care Excellence (NICE) …

Background Antidepressants are among the most commonly prescribed drugs worldwide.
They are often discontinued, frequently without the knowledge of the prescribing physician. It …

Adaptation of the brain to the presence of a drug predicts withdrawal on cessation. The
outcome of adaptation is often referred to as 'physical dependence'in pharmacology, as …

The value of a prospective assessment of discontinuation-emergent symptoms proximal to
the termination of antidepressant treatment cannot be overstated. Though varying in …

Despite marked increases in antidepressant drug prescriptions over the last 3 decades, the
burden and disability attributed to major depression are still on the rise. This calls into …

Twenty eight patients treated with selective serotonin reuptake inhibitors/venlafaxine were
randomized to a three-day (short) or 14-day (longer) anti—depressant taper and openly …

Strong evidence supports the existence of a discontinuation syndrome following the
withdrawal of antidepressant medication, particularly second-generation antidepressants …