Purpose: To compare the changes in human tear proteome and clinical effects following
topical cyclosporine A (CsA) 0.05% or diquafosol tetrasodium (DQS) 3% treatment of dry eye …

Purpose To identify specific dry eye disease (DED) tear biomarker (s) using tear proteomic
analysis, clinical parameters, and their correlations before and after DED treatment. Methods …

Purpose It was hypothesized that tear protein biomarkers could predict the effects of topical
steroid treatment and desiccating stress in patients with dry eye disease (DED). To test this …

Purpose: To evaluate the efficacy of commonly used biomarkers in dry eye disease
management in a longitudinal observational case series study followed by an interventional …

Purpose To evaluate the effect of 0.1%-fluorometholone (FML) on tear inflammatory
molecule levels after 22-days treatment in dry eye disease (DED) patients exposed to an …

Tear film alterations in dry eye disease (DED) include reduced tear volume and an increase
in inflammatory cytokines. Instability and reduced tear production initiate a vicious cycle …

Purpose To compare the treatment effects of topical cyclosporine A (CsA) and diquafosol
sodium (DQS) for the treatment of moderate to severe dry eye disease (DED). Methods This …

Dry eye disease (DED) is a commonly occurring, multifactorial disease characterized by
reduced tear film stability and hyperosmolarity at the ocular surface, leading to discomfort …

Homeostasis of the lacrimal functional unit is needed to ensure a well-regulated ocular
immune response comprising innate and adaptive phases. When the ocular immune system …

Most studies about dry eye disease (DED) chose unilateral eye for investigation and drew
conclusions based on monocular results, whereas most studies involving tear proteomics …