Candida morphogenesis and host–pathogen interactions

M Whiteway, U Oberholzer - Current opinion in microbiology, 2004 - Elsevier
The human fungal pathogen Candida albicans has many morphological forms. Recent
advances in genomics and cell biology are providing an improved understanding of the …

Coevolution of morphology and virulence in Candida species

DS Thompson, PL Carlisle, D Kadosh - Eukaryotic cell, 2011 - Am Soc Microbiol
Many of the major human fungal pathogens are known to undergo morphological changes,
which in certain cases are associated with virulence. Although there has been an intense …

Regulatory mechanisms controlling morphology and pathogenesis in Candida albicans

D Kadosh - Current opinion in microbiology, 2019 - Elsevier
Highlights•There is a strong association between C. albicans morphology and virulence.•C.
albicans morphology control mechanisms may serve as important antifungal …

Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens

J Sharma, S Rosiana, I Razzaq, RS Shapiro - Journal of Fungi, 2019 - mdpi.com
Fungal infections are a growing public health concern, and an increasingly important cause
of human mortality, with Candida species being amongst the most frequently encountered of …

Morphogenesis in Candida albicans

M Whiteway, C Bachewich - Annu. Rev. Microbiol., 2007 - annualreviews.org
Candida albicans is termed a dimorphic fungus because it proliferates in either a yeast form
or a hyphal form. The switch between these forms is the result of a complex interplay of …

[HTML][HTML] Candida pathogenesis: unravelling the threads of infection

BE Corner, PT Magee - Current Biology, 1997 - cell.com
Candida pathogenesis: Unravelling the threads of infection: Current Biology Skip to Main
Content Advertisement Current Biology This journal offers authors two options (open access or …

The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage

D Wilson, JR Naglik, B Hube - PLoS pathogens, 2016 - journals.plos.org
Fungal pathogens are more commonly associated with morbidity and mortality than
generally appreciated. In fact, a significant portion of the world population is infected by …

Contributions of hyphae and hypha‐co‐regulated genes to Candida albicans virulence

CA Kumamoto, MD Vinces - Cellular microbiology, 2005 - Wiley Online Library
The fascinating ability of Candida albicans to undergo dramatic changes in cellular
morphology has invited speculation that this plasticity in form contributes to the virulence of …

Regulatory networks controlling Candida albicans morphogenesis

AJP Brown, NAR Gow - Trends in microbiology, 1999 - cell.com
Candida albicans undergoes reversible morphogenetic transitions between budding,
pseudohyphal and hyphal growth forms that promote the virulence of this pathogenic …

Comparative evolution of morphological regulatory functions in Candida species

E Lackey, G Vipulanandan, DS Childers… - Eukaryotic cell, 2013 - Am Soc Microbiol
Morphological transitions play an important role in virulence and virulence-related
processes in a wide variety of pathogenic fungi, including the most commonly isolated …