Erlotinib in patients with advanced non-small-cell lung cancer: impact of dose reductions and a novel surrogate marker
D Binder, AC Buckendahl, RH Hübner, P Schlattmann… - Medical Oncology, 2012 - Springer
Erlotinib is a relatively well-tolerated treatment option for patients with advanced non-small-
cell lung cancer (NSCLC). Some patients suffer from severe skin toxicity or diarrhea, making …
cell lung cancer (NSCLC). Some patients suffer from severe skin toxicity or diarrhea, making …
Safety profiles of erlotinib therapy in patients with advanced non-small-cell lung cancer
K Hotta, K Kiura - Expert review of anticancer therapy, 2011 - Taylor & Francis
Erlotinib is an orally available, small-molecule EGF receptor tyrosine kinase inhibitor. It has
shown promising activity in chemotherapy-relapsed patients with advanced non-small-cell …
shown promising activity in chemotherapy-relapsed patients with advanced non-small-cell …
Erlotinib for frontline treatment of advanced non–small cell lung cancer: a phase II study
G Giaccone, M Gallegos Ruiz, T Le Chevalier… - Clinical Cancer …, 2006 - AACR
Purpose: Erlotinib has proven activity in pretreated patients with advanced non–small cell
lung cancer (NSCLC). We evaluated erlotinib in the frontline treatment of advanced NSCLC …
lung cancer (NSCLC). We evaluated erlotinib in the frontline treatment of advanced NSCLC …
Final survival and safety results from a multicenter, open‐label, phase 3b trial of erlotinib in patients with advanced nonsmall cell lung cancer
DR Spigel, M Lin, V O'Neill… - … International Journal of …, 2008 - Wiley Online Library
BACKGROUND. Erlotinib is an orally available, reversible inhibitor of epidermal growth
factor receptor (EGFR) with a proven survival advantage for patients with locally advanced …
factor receptor (EGFR) with a proven survival advantage for patients with locally advanced …
Erlotinib monotherapy in patients with advanced non-small cell lung cancer: an effective approach with low toxicity
A Ardavanis, S Koumna, I Fragos, S Malliou… - Anticancer …, 2008 - ar.iiarjournals.org
Background: Treatment of non-small cell lung cancer (NSCLC) with tyrosine kinase
inhibitors (TKIs) of epidermal growth factor receptor (EGFR) and particularly erlotinib …
inhibitors (TKIs) of epidermal growth factor receptor (EGFR) and particularly erlotinib …
Efficacy vs. effectiveness: erlotinib in previously treated non-small-cell lung cancer
N Sheikh, CR Chambers - Journal of Oncology Pharmacy …, 2013 - journals.sagepub.com
Background: A randomized trial carried out by Shepherd et al. in patients with advanced or
metastatic non-small-cell lung cancer showed statistically significant benefit of erlotinib over …
metastatic non-small-cell lung cancer showed statistically significant benefit of erlotinib over …
[HTML][HTML] Efficacy and safety of erlotinib monotherapy for Japanese patients with advanced non-small cell lung cancer: a phase II study
K Kubota, Y Nishiwaki, T Tamura, K Nakagawa… - Journal of Thoracic …, 2008 - Elsevier
Introduction The aim of this study was to evaluate the efficacy and safety of Erlotinib in
Japanese patients with previously treated non-small cell lung cancer (NSCLC). Available …
Japanese patients with previously treated non-small cell lung cancer (NSCLC). Available …
Erlotinib: as maintenance monotherapy in non-small-cell lung cancer
VJ Muir, S Dhillon - BioDrugs, 2011 - Springer
Erlotinib is a low molecular weight, orally active, epidermal growth factor receptor (EGFR)
tyrosine kinase inhibitor. Inhibition of EGFR tyrosine kinase results in the disruption of …
tyrosine kinase inhibitor. Inhibition of EGFR tyrosine kinase results in the disruption of …
Erlotinib in first-line therapy for non-small cell lung cancer: a prospective phase II study
DR Choi, DH Lee, CM Choi, SW Kim, C Suh… - Anticancer …, 2011 - ar.iiarjournals.org
Background: This phase II study evaluated efficacy of first-line erlotinib therapy for chemo-
naïve patients with non-small cell lung cancer (NSCLC) by their clinicopathological and/or …
naïve patients with non-small cell lung cancer (NSCLC) by their clinicopathological and/or …
Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer
T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
To evaluate the efficacy and safety of erlotinib for non-small cell lung cancer (NSCLC), we
performed a population-based observational study. The study involved 307 patients treated …
performed a population-based observational study. The study involved 307 patients treated …
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