Purified bovine nasal cartilage proteoglycans (aggregate and subunit containing fractions)
and to a lesser degree, chondroitin 4-sulfate of physiological size, retard seeded …

Proteoglycans extracted from nasal and articular cartilages have previously been shown to
inhibit hydroxyapatite proliferation in vitro. This study now demonstrates that proteoglycans …

The calcification of connective tissues, including cartilage, is under the control of many
interacting systems. Proteoglycans are thought to retard the deposition of hydroxyapatite …

The effect of cartilage proteoglycans on HA seed crystal growth was studied using a system
providing constant supersaturation with respect to HA. The monomers were much less …

Well-characterized bovine nasal proteoglycan A1 fraction (aggregate) and proteoglycan D1
fraction (subunit) have been shown to be effective inhibitors of hydroxyapatite (HA) formation …

The small leucine-rich proteoglycans (SLRPs) interact with hydroxyapatite (HAP) and have
been demonstrated to be important modulators of mineralisation. In the present study we …

Proteoglycans from bovine nasal septa and from the Swarm rat chondrosarcoma were
isolated as aggregates (PGC) and as monomers (PGS). Portions of the PGC preparations …

Proteoglycans from the brachymorphic (bm/bm) mouse have a reduced sulfate content due
to the impaired activity of adenosine phosphosulfate phosphokinase in these animals. X-ray …

Crystal growth in native collagen gels has been used to determine the role of extracellular
matrix macromolecules in biological calcification phenomena. In this system, type I collagen …

The interaction of hyaluronan (Mr range 80–120 X 10 4) with poorly crystalline
hydroxyapatite, such as is found in calcified cartilage and bone, was studied to challenge …