The ability to sequence genomes from ancient biological material has provided a rich source
of information for evolutionary biology and engaged considerable public interest. Although …

Over the past decade, a genomics revolution, made possible through the development of
high-throughput sequencing, has triggered considerable progress in the study of ancient …

The last century has witnessed progress in the study of ancient infectious disease from
purely medical descriptions of past ailments to dynamic interpretations of past population …

Ancient bacterial and viral genomes provide a window into the tempo, chronology, and rate
of evolutionary processes of pathogens that have accompanied humans throughout history …

This perspective draws on the record of ancient pathogen genomes and microbiomes
illuminating patterns of infectious disease over the course of the Holocene in order to …

Disease is a major cause of natural selection affecting human evolution, whether through a
sudden pandemic or persistent morbidity and mortality. Recent contributions in the field of …

The recent use of next-generation sequencing methods to investigate historical disease
outbreaks has provided us with an unprecedented ability to address important and long …

The study of ancient disease can now include direct analyses of all or part of the genomes of
pathogens through ancient DNA techniques. Such analyses are challenging since due to …

Next generation sequencing (NGS) has unlocked access to the wide range of non-cultivable
microorganisms, including those present in the ancient past. The study of microorganisms …

The detection of ancient microbial DNA offers a new approach for the study of infectious
diseases, their occurrence, frequency and host–pathogen interaction in historic times and …