[HTML][HTML] Purification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae)

JM Conlon, L Guilhaudis, S Attoub, L Coquet… - Antibiotics, 2023 - mdpi.com
Frogs from the extensive amphibian family Hylidae are a rich source of peptides with
therapeutic potential. Peptidomic analysis of norepinephrine-stimulated skin secretions from …

[HTML][HTML] Multifunctional host-defense peptides isolated from skin secretions of the banana tree dwelling frog Boana platanera (Hylidae; Hylinae)

JM Conlon, A Sridhar, D Khan, TS Cunning… - Biochimie, 2024 - Elsevier
Five host-defense peptides (figainin 2PL, hylin PL, raniseptin PL, plasticin PL, and peptide
YL) were isolated from norepinephrine-stimulated skin secretions of the banana tree …

Peptidomic analysis of the host-defense peptides in skin secretions of the Trinidadian leaf frog Phyllomedusa trinitatis (Phyllomedusidae)

M Mechkarska, L Coquet, J Leprince… - … and Physiology Part D …, 2018 - Elsevier
Peptidomic analysis (reversed-phase HPLC combined with MALDI-TOF mass spectrometry
and automated Edman degradation) of norepinephrine-stimulated skin secretions from the …

The hymenochirins: A family of host-defense peptides from the Congo dwarf clawed frog Hymenochirus boettgeri (Pipidae)

M Mechkarska, M Prajeep, L Coquet, J Leprince… - Peptides, 2012 - Elsevier
Skin secretions of frogs from the subfamily Xenopodinae (Xenopus+ Silurana) within the
family Pipidae are a rich source of antimicrobial peptides with therapeutic potential but …

[HTML][HTML] Peptidomic analysis of the host-defense peptides in skin secretions of the Amazon River frog Lithobates palmipes (Ranidae)

M Mechkarska, G Barran, J Kolodziejek… - … and Physiology Part D …, 2023 - Elsevier
Skin secretions of certain frog species represent a source of host-defense peptides (HDPs)
with therapeutic potential and their primary structures provide insight into taxonomic and …

Identification and characterization of novel host defense peptides from the skin secretion of the fungoid frog, Hydrophylax bahuvistara (Anura: Ranidae)

TPVK Vineeth Kumar, R Asha, G Shyla… - Chemical biology & …, 2018 - Wiley Online Library
Two novel peptides (brevinin1 HY ba1 and brevinin1 HY ba2) were identified from the skin
secretion of the frog Hydrophylax bahuvistara, endemic to Western Ghats, India, and their …

Structure and function of cationic hylin bioactive peptides from the tree frog Boana pulchella in interaction with lipid membranes

S Aguilar, AE Brunetti, AV Garay, LC Santos, LO Perez… - Peptides, 2023 - Elsevier
Amphibians have a great diversity of bioactive peptides in their skin. The cDNA prepro-
peptide sequencing allowed the identification of five novel mature peptides expressed in the …

Purification of peptides with differential cytolytic activities from the skin secretions of the Central American frog, Lithobates vaillanti (Ranidae)

JM Conlon, H Raza, L Coquet, T Jouenne… - … and Physiology Part C …, 2009 - Elsevier
Peptide-based defenses of ranid frogs from Mexico and Central America have been studied
in much less detail than those from North America. Peptides belonging to the brevinin-1 (5 …

Structural and positional studies of the antimicrobial peptide brevinin‐1BYa in membrane‐mimetic environments

PB Timmons, D O'Flynn, JM Conlon… - Journal of Peptide …, 2019 - Wiley Online Library
Abstract Brevinin‐1BYa (FLPILASLAAKFGPKLFCLVTKKC), first isolated from skin
secretions of the foothill yellow‐legged frog Rana boylii, shows broad‐spectrum activity …

Hylin a1, the first cytolytic peptide isolated from the arboreal South American frog Hypsiboas albopunctatus (“spotted treefrog”)

MS Castro, TCG Ferreira, EM Cilli, E Crusca Jr… - Peptides, 2009 - Elsevier
RP-HPLC fractionation of the electrically stimulated skin secretion of the arboreal South
American frog Hypsiboas albopunctatus (“spotted treefrog”) led to the isolation of a cytolytic …