Septins are able to polymerize into long apolar filaments and have long been considered to
be a component of the cytoskeleton alongside intermediate filaments (which are also apolar …

In order to fully understand any complex biochemical system from a mechanistic point of
view, it is necessary to have access to the three-dimensional structures of the molecular …

Septins form a conserved family of filament forming GTP binding proteins found in a wide
range of eukaryotic cells. They share a common structural architecture consisting of an N …

Mammalian septins are a family of guanosine triphosphate-binding proteins thought to play
a role in a number of key cellular processes, such as cytokinesis, protein scaffolding and …

Septins are an example of subtle molecular recognition whereby different paralogues must
correctly assemble into functional filaments important for essential cellular events such as …

Septins are a family of proteins highly conserved in eukaryotes that have been under
intense scrutiny lately because they appear to comprise a novel component of the …

The human genome codes for 13 members of a family of filament-forming GTP-binding
proteins known as septins. These have been divided into four different subgroups on the …

The septins are filament‐forming proteins found in diverse eukaryotes from fungi to
vertebrates, with roles in cytokinesis, shaping of membranes and modifying cytoskeletal …

Septins are a conserved family of polymerizing guanine nucleotide binding proteins
associated with diverse processes in dividing and non-dividing cells. In humans, 12 septin …

Protein-protein interactions play a critical role in promoting the stability of protein quaternary
structure and in the assembly of large macromolecular complexes. What drives the …