Hyperuricemia may occur when there is an excess of uric acid in the blood. Hyperuricemia
may result from increased production or decreased excretion of uric acid. Elevated uric acid …

Uric acid is the final product of purine metabolism. Hyperuricemia is defined as a condition
where the level of uric acid exceeds the normal range. The most well-known disease …

Hyperuricemia (elevated serum uric acid) is prevalent, and an important mediator of gout, an
increasingly common condition. In addition, hyperuricemia is associated with metabolic …

Gout is the most common form of inflammatory arthritis and is a multifactorial disease
typically characterized by hyperuricemia and monosodium urate crystal deposition …

Hyperuricemia is caused by reduced renal/extrarenal excretion and overproduction of uric
acid. It is affected by genetic predisposition related to uric acid transporters and by visceral …

Purine metabolism in the circulatory system yields uric acid as its final oxidation product,
which is believed to be linked to the development of gout and kidney stones. Hyperuricemia …

Over the past decade, significant advances have been made regarding the pathogenesis,
clinical implications, and treatment of hyperuricemia. While physicians have understood for …

Introduction Hyperuricemia is an overlooked cardiovascular and renal risk factor.
Epidemiological and genetic studies have shown an independent role of uric acid in the risk …

Hyperuricemia, ie increased serum uric acid (UA) concentration, is a common problem in
clinical practice. While there are clear guidelines concerning management of symptomatic …

Uric acid is the end product of purine metabolism in humans. High levels are causative in
gout and urolithiasis. Hyperuricaemia has also been implicated in the pathophysiology of …