Immunohistochemical characterization of the distribution of GABAA receptor subunits γ1/3
and 2 in the hippocampus relative to neurofibrillary tangle (NFT) pathology staging was …

Alzheimer's disease (AD) is characterized by selective vulnerability of specific neuronal
populations within particular brain regions. For example, hippocampal glutamatergic cell …

Alterations in the γ-aminobutyric acid (GABA) neurotransmitter and receptor systems may
contribute to vulnerability of hippocampal pyramidal neurons in Alzheimer's disease (AD) …

Immunocytochemical techniques were employed to examine the distribution of the γ-
aminobutyric acid (GABA) A receptor α1 subunit within the hippocampus of 19 elderly …

Gamma‐aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central
nervous system. GABA type A receptors (GABAAR s) are severely affected in Alzheimer's …

In AD, it is hypothesized that one factor contributing to the vulnerability of neurons is a
delicate balance of excitatory and inhibitory inputs. To examine this hypothesis we have …

Our work on the role of glutamate in Alzheimer's disease (AD)-related neuronal vulnerability
and death provided significant insight into the potential contribution of the γ-aminobutyric …

We employed in situ hybridization and quantitative densitometry techniques to examine
hippocampal mRNA expression of GABAA receptor subunits α1 and α5 in human subjects …

GABAB and GABAA binding sites were evaluated by quantitative autoradiography of 3H-
GABA binding in superior frontal gyrus of persons who died with dementia of the Alzheimer's …

GABA is the primary inhibitory neurotransmitter in the nervous system. GABAA receptors
(GABAARs) are pentameric ionotropic channels. Subunit composition of the receptors is …