Hepatotoxicity induced by PPⅥ and PPⅦ in zebrafish were related to the Cholesterol disorder

Z Li, Y Tang, Z Liu, Q Fan, M Chen, Z Lin, C Zhao, R Lin - Phytomedicine, 2022 - Elsevier
Abstract Background PPⅥ 2 and PPⅦ 3 were a group of Pennogenin compounds extracted
from the Paris polyphylla and caused hepatotoxicity in human, while the potential underlying …

Environmentally relevant concentrations of tris (2-chloroethyl) phosphate (TCEP) induce hepatotoxicity in zebrafish (Danio rerio): a whole life-cycle assessment

F Hu, W Li, H Wang, H Peng, J He, J Ding… - Fish Physiology and …, 2023 - Springer
Abstract Tris (2-chloroethyl) phosphate (TCEP), a typical organophosphate flame retardant,
is of increasingly great concern considering their ubiquitous presence in aquatic …

Integration of Transcriptomics and Metabolomics for Evaluating Changes in the Liver of Zebrafish Exposed to a Sublethal Dose of Cyantraniliprole

L Zhao, H Zhang, Z Niu, D Wei, S Yan, J Bai, L Zhang… - Water, 2023 - mdpi.com
Diamide insecticides are a class of insecticides with high efficiency, a broad spectrum, and
environmental and ecological safety. However, their effect on the environment cannot be …

Differential mechanisms regarding triclosan vs. bisphenol A and fluorene-9-bisphenol induced zebrafish lipid-metabolism disorders by RNA-Seq

L Sun, Y Ling, J Jiang, D Wang, J Wang, J Li, X Wang… - Chemosphere, 2020 - Elsevier
Exposure of endocrine disrupting chemicals (EDCs) is closely related to induction of obesity,
nonalcoholic fatty liver disease (NAFLD) and other lipid-metabolism diseases. Herein, we …

Effects of sublethal concentration of metamifop on hepatic lipid metabolism in adult zebrafish (Danio rerio)

F Zhao, M Zhang, M Guo, M Duan, J Zheng, X Chen… - Aquatic Toxicology, 2021 - Elsevier
Metamifop (MET) is an effective herbicide that has been extensively used in paddy fields.
Previous research demonstrated that MET was highly toxic to zebrafish embryos, and this …

[HTML][HTML] Iprodione induces hepatotoxicity in zebrafish by mediating ROS generation and upregulating p53 signalling pathway

W Hu, G Chen, W Yuan, C Guo, F Liu, S Zhang… - Ecotoxicology and …, 2024 - Elsevier
Iprodione is an effective and broad-spectrum fungicide commonly used for early disease
control in fruit trees and vegetables. Due to rainfall, iprodione often finds its way into water …

Acute exposure to tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) causes hepatic inflammation and leads to hepatotoxicity in zebrafish

C Liu, G Su, JP Giesy, RJ Letcher, G Li, I Agrawal… - Scientific reports, 2016 - nature.com
Abstract Tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) has been frequently detected in
environmental media and has adverse health effect on wildlife and humans. It has been …

Transcriptome analysis reveals hepatotoxicity in zebrafish induced by cyhalofop‑butyl

M Duan, X Guo, X Chen, M Guo, M Zhang, H Xu… - Aquatic Toxicology, 2022 - Elsevier
Cyhalofop‑butyl is a highly effective aryloxyphenoxypropionate herbicide and widely used
for weed control in paddy fields. With the increasing residue of cyhalofop‑butyl, it poses a …

Inflammation aggravated the hepatotoxicity of triptolide by oxidative stress, lipid metabolism disorder, autophagy, and apoptosis in zebrafish

C Li, C Zhang, C Zhu, J Zhang, Q Xia, K Liu… - Frontiers in …, 2022 - frontiersin.org
Triptolide is a major compound isolated from the Tripterygium wilfordii Hook that is mainly
used for the treatment of autoimmune disorders and inflammatory diseases. Though …

Biomarker Responses, Gene Expression Alterations, and Histological Changes in Zebrafish (Danio rerio) After In Vivo Exposure to Polychlorinated Diphenyl Ethers

C Ye, W Xiong, S Shi, J Shi, W Yang… - Frontiers in Physiology, 2022 - frontiersin.org
Polychlorinated diphenyl ethers (PCDEs) have been detected in various aquatic matrices,
which pose potential threats to aquatic ecosystem security. In this work, both micro and …