Simvastatin (SV) is a typical lipid-lowering agent detected widely in waters, so its latent toxic
effects to fish are deserved of concern. The purposes of this study aim at revealing the …

Polyphyllin I (PPI) and polyphyllin II (PII) are the main active substances in the Paris
polyphylla. However, liver toxicity of these compounds has impeded their clinical application …

Long-term exposure of triclosan (TCS), an important antimicrobial agent, can lead to
deleterious effects on liver growth and development. However, the related mechanisms on …

Triclosan (TCS) is widely used in personal care products, and its chronic exposure leads to
severely toxic effects in zebrafish (Danio rerio). PKCα, Nrf2 and p53 are three important …

The combined pollution of microplastics (MPs) and sulfamethoxazole (SMZ) often occurs in
aquatic ecosystems, posing a serious threat to animal and human health. However, little is …

Phytolacca acinosa Roxb (PAR), a traditional Chinese medicine, has been widely used as a
diuretic drug for a long period of time for the treatment edema, swelling, and sores. However …

Cyhalofop-butyl (CyB) is a highly effective herbicide and is widely used for weed control in
paddy fields. Because CyB is easily residual in the aquatic environment, its potential harm to …

The ubiquitous environmental presence of tris (2-chloroethyl) phosphate (TCEP) poses a
potential threat to animals; however, little is known about its hepatotoxicity. In this study, the …

Endocrine disrupting chemicals (EDCs) can disrupt normal endocrine function by interfering
with the synthesis and release of hormones, causing adverse reactions to development …

Phenanthrene (PHE) is a common polycyclic aromatic hydrocarbon (PAH) in aquatic
environments, and this contaminant can cause adverse effects on teleostean performance …