Molecular mechanism of apoptosis induced by 4-tBP in common carp (Cyprinus carpio L.) head kidneys was explored from various angles: Hippo pathway, miR-203a …
J Liang, X Lin, C Jiang, Y Liu, Z Hao, M Qiu, X Liu… - Aquaculture, 2024 - Elsevier
tert butylphenol (4-tBP), a toxic environmental pollutant estrogen, received widespread
attention due to its widespread presence, environmental persistence, and toxic effect …
attention due to its widespread presence, environmental persistence, and toxic effect …
Oxidative stress, cell cycle arrest, DNA damage and apoptosis in adult zebrafish (Danio rerio) induced by tris (1, 3-dichloro-2-propyl) phosphate
H Chen, P Wang, Z Du, G Wang, S Gao - Aquatic Toxicology, 2018 - Elsevier
Abstract Tris (1, 3-dichloro-2-propyl) phosphate (TDCPP) is an additive flame retardant of
high production volume, and frequently detected in biota and environment. However …
high production volume, and frequently detected in biota and environment. However …
Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism
F Yadetie, OA Karlsen, M Eide, C Hogstrand… - BMC genomics, 2014 - Springer
Abstract Background Polychlorinated biphenyls (PCBs) are persistent organic pollutants
(POPs) with harmful effects in animals and humans. Although PCB 153 is one of the most …
(POPs) with harmful effects in animals and humans. Although PCB 153 is one of the most …
[HTML][HTML] Metabolic characteristics of evodiamine were associated with its hepatotoxicity via PPAR/PI3K/AKT/NF-кB/tight junction pathway-mediated apoptosis in …
Q Fan, R Liang, M Chen, Z Li, X Tao, H Ren… - Ecotoxicology and …, 2024 - Elsevier
Evodiae Fructus (EF), an herbal medicine, possesses remarkable anti-inflammatory and
analgesic properties. It exhibits insecticidal activity as a potent insecticide candidate …
analgesic properties. It exhibits insecticidal activity as a potent insecticide candidate …
[HTML][HTML] Insights into the sex-dependent reproductive toxicity of 2-ethylhexyl diphenyl phosphate on zebrafish (Danio rerio)
R Yang, X Wang, J Wang, P Chen, Q Liu… - Environment …, 2022 - Elsevier
As a frequently detected organophosphate ester in various environmental media, the toxic
effects of 2-ethylhexyl diphenyl phosphate (EHDPHP) on aquatic organisms of different …
effects of 2-ethylhexyl diphenyl phosphate (EHDPHP) on aquatic organisms of different …
Effects of simvastatin on the PXR signaling pathway and the liver histology in Mugilogobius abei
C Wang, P Ku, X Nie, S Bao, Z Wang, K Li - Science of The Total …, 2019 - Elsevier
Simvastatin is one of the most commonly cholesterol-lowering prescribed drugs all over the
world. With the increase of consumption of these pharmaceuticals and subsequent their …
world. With the increase of consumption of these pharmaceuticals and subsequent their …
Chronic exposure to 3, 6-dichlorocarbazole exacerbates non-alcoholic fatty liver disease in zebrafish by disrupting lipid metabolism and inducing special lipid …
C Hou, M Huang, P Wang, Q Zhang, G Wang, S Gao - Chemosphere, 2024 - Elsevier
Most previous studies have focused primarily on the adverse effects of environmental
chemicals on organisms of good healthy. Although global prevalence of non-alcoholic fatty …
chemicals on organisms of good healthy. Although global prevalence of non-alcoholic fatty …
Transcriptome analysis to assess the cholestatic hepatotoxicity induced by Polygoni Multiflori Radix: Up-regulation of key enzymes of cholesterol and bile acid …
LL Jiang, DS Zhao, YX Fan, Q Yu, YS Lai, P Li… - Journal of proteomics, 2018 - Elsevier
Abstract Polygoni Multiflori Radix (PMR) has been commonly used as a tonic in China for
centuries. However, PMR-associated hepatotoxicity is becoming a safety issue. Cholestasis …
centuries. However, PMR-associated hepatotoxicity is becoming a safety issue. Cholestasis …
[HTML][HTML] Systems assessment of statins hazard: Integrating in silico prediction, developmental toxicity profile and transcriptomics in zebrafish
Y Han, Y Ma, J Tong, J Zhang, C Hu - Ecotoxicology and Environmental …, 2022 - Elsevier
Statins are prescribed widely as lipid-lowering agents. However, statins are associated with
an increased harmful risk on public health and the ecosystem. Little is known about statins' …
an increased harmful risk on public health and the ecosystem. Little is known about statins' …
Pretilachlor has the potential to induce endocrine disruption, oxidative stress, apoptosis and immunotoxicity during zebrafish embryo development
J Jiang, Y Chen, R Yu, X Zhao, Q Wang… - Environmental toxicology …, 2016 - Elsevier
The objectives of the present study were to investigate the toxic effects of pretilachlor on
zebrafish during its embryo development. The results demonstrated that the transcription of …
zebrafish during its embryo development. The results demonstrated that the transcription of …