Temporal transcriptome analysis in female scallop Chlamys farreri: First molecular insights into the disturbing mechanism on lipid metabolism of reproductive-stage …

R Xu, L Pan, Y Yang, Y Zhou, D Li - Science of the Total Environment, 2020 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are one of the most widespread persistent organic
pollutants (POPs) in marine environment. Benzo [a] pyrene (B [a] P), the most toxic …

Single-cell transcriptomic analysis reveals heterogeneity of the patterns of responsive genes and cell communications in liver cell populations of zebrafish exposed to …

J Deng, X Zeng, J Li, L Luo, Y Yang, T Luan - Science of The Total …, 2023 - Elsevier
Nanoplastics (NPs) are a group of emerging environmental pollutants with potential toxicity
and health risk on biosystem and ecosystem. Great efforts have been devoted to describing …

Transcriptome changes of Takifugu obscurus liver after acute exposure to phenanthrene

SL Jiang, DA Fang, DP Xu - Physiological Genomics, 2021 - journals.physiology.org
Phenanthrene (Phe) is a model compound in polycyclic aromatic hydrocarbon (PAH)
research. Reportedly, Phe treatment induced oxidative stress and histological disorders to …

Exposure to 2, 3, 3′, 4, 4′, 5-hexachlorobiphenyl promotes nonalcoholic fatty liver disease development in C57BL/6 mice

Q Shan, N Chen, W Liu, F Qu, A Chen - Environmental Pollution, 2020 - Elsevier
Previous in vitro studies have indicated that 2, 3, 3′, 4, 4′, 5-hexachlorobiphenyl (PCB
156) may be a new contributor to metabolic disruption and may further cause the occurrence …

Fraxinellone induces hepatotoxicity in zebrafish through oxidative stress and the transporters pathway

S Wang, J Bao, J Li, W Li, M Tian, C Qiu, F Pang, X Li… - Molecules, 2022 - mdpi.com
Fraxinellone (FRA), a major active component from Cortex Dictamni, produces
hepatotoxicity via the metabolization of furan rings by CYP450. However, the mechanism …

Assessing potential liver injury induced by Polygonum multiflorum using potential biomarkers via targeted sphingolipidomics

Z Jia, L Liu, J Liu, C Fang, M Pan, J Zhang… - Pharmaceutical …, 2022 - Taylor & Francis
Abstract Context Polygonum multiflorum Thunb.(Polygonaceae)(PM) can cause potential
liver injury which is typical in traditional Chinese medicines (TCMs)-induced hepatotoxicity …

Toxic effects and transcriptome analyses of zebrafish (Danio rerio) larvae exposed to benzophenones

Q Meng, K Yeung, ML Kwok, CT Chung, XL Hu… - Environmental …, 2020 - Elsevier
Sunscreen chemicals, such as benzophenones (BPs), are common environmental
contaminants that are posing a growing health concern due to their increasing presence in …

[HTML][HTML] Alteration of lipid metabolism, autophagy, apoptosis and immune response in the liver of common carp (Cyprinus carpio) after long-term exposure to …

Z Gu, R Jia, Q He, L Cao, J Du, W Feng, G Jeney… - Ecotoxicology and …, 2021 - Elsevier
Bisphenol A (BPA), as a phenolic compound, is harmful to human health, and its residue in
the aquatic environment also threatens the health of aquatic animals. In this research, the …

[HTML][HTML] Ecotoxicological response of zebrafish liver (Danio rerio) induced by di-(2-ethylhexyl) phthalate

X Li, Q Wang, C Wang, Z Yang, J Wang, L Zhu… - Ecological …, 2022 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) has become a ubiquitous contaminant in
aquatic environments due to its increasing utilization in recent years. Although its …

Exploring the endocrine disrupting potential of a complex mixture of PAHs in the estrogen pathway in Oreochromis niloticus hepatocytes

TL de Souza, JZ da Luz, A de Almeida Roque… - Aquatic Toxicology, 2024 - Elsevier
This study aimed to investigate the toxicity and endocrine disrupting potential of a complex
mixture of polycyclic aromatic hydrocarbons (PAHs) in the estrogen pathway using …